ISRCTN10248064已完成2 期
Intermittent high dose AmBisome® on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa: An adaptive randomized controlled non-inferiority trial
St George's University of London (UK)0 个研究点目标入组 80 人开始时间: 2014年1月22日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 80
研究概览
简要总结
2015 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/26081985 2020 results in https://www.ncbi.nlm.nih.gov/pubmed/29945252 (added 10/03/2020)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Consecutive patients (male and female) aged > 18 years with a first episode of cryptococcal meningitis (CSF India ink or CrAg test)
- •2. Known to be HIV positive or willing to undertake an HIV test
- •3. Willing to agree to participate in the study
排除标准
- •1. Pregnancy or lactation
- •2. Previous serious reaction to study drugs
- •3. Already taking antifungals for >48 hours
- •4. Concomitant medication that is contraindicated with study drugs
研究者
相似试验
已完成
4 期
Safety and Effectiveness of Short-course AmBisome in the Treatment of PKDL in BangladeshPost-kala-azar Dermal LeishmaniasisNCT03311607Medecins Sans Frontieres, Netherlands280
终止
4 期
Ambisome and Management of Culture-negative Neutropenic Fever Unresponsive to AntibioticsFebrile NeutropeniaNCT00421187Gilead Sciences20
已完成
4 期
CRITIC - Treatment of Candidemia and Invasive CandidiasisCandidemiaInvasive CandidiasisNCT00670657Gilead Sciences39
已完成
4 期
Comparing different dosing regimens of Avastin® in the treatment of wet age-related macular degeneratioISRCTN95654194ottingham University Hospitals NHS Trust (UK)812
已完成
不适用
A randomised trial of high dose therapy and autologous bone marrow transplantation versus continuing conventional combination chemotherapy for adults with lymphoblastic lymphomaymphoma (non-Hodgkin's) cancerLymphoma (non-Hodgkin's)CancerISRCTN58831878Cancer Research UK (CRUK) (UK)119