Diagnostic Performance of Mansoura Scoring System in Predicting Spontaneous Bacterial Peritonitis in Patients With Chronic Liver Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 94
- 试验地点
- 1
- 主要终点
- Diagnosis of Spontaneous Bacterial Peritonitis- Correlation Between Mansoura Scoring System Vs Ascitic Fluid Analysis: Yes/no
研究概览
简要总结
The study will be aimed at the diagnostic performance of Mansoura Scoring System in predicting Spontaneous Bacterial Peritonitis (SBP) in patients with chronic liver disease
Objectives
1. To compare Mansoura scoring in SBP and non SBP groups.
2. To correlate Mansoura scoring with other ascitic parameters like Total counts, differential counts, protein, albumin, culture positivity, etc. in patients with decompensated liver disease cirrhosis in SBP and non SBP groups.
3. To compare individual parameters of scoring system i.e. Mean Platelet Volume, Neutrophil Lymphocyte Ratio and C Reactive Protein in SBP and non SBP groups.
4. To correlate Mansoura scoring in survival and non survival group in patients with SBP.
5. To correlate Mansoura scoring with incidence of Acute Kidney injury in SBP and non SBP groups.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Any patient diagnosed with Spontaneous Bacterial Peritonitis (SBP) as paracentesis showing PMN ≥ 250 cells/mm3 and/or positive ascitic fluid culture.
排除标准
- •Patients who had received antibiotic and/or prophylaxis for SBP at least 1 month before admission
- •Patients who had other causes of ascites, for example, pancreatitis, peritoneal carcinomatosis, tuberculosis, congestive heart failure, renal diseases, or hemorrhage into ascites and/or patients with secondary peritonitis
- •Malignancy
- •Hematological diseases
- •Received antiplatelet medications atheist 1 month before their admission
- •Conditions associated with increased MPV, for example, thyroid disorders, peripheral vascular disease
- •Active hemorrhage
- •Infused with platelet or blood at least 1 month before their admission
- •Received bone marrow transplantation/chemotherapy/ radiotherapy 1 month before admission
- •Immunocompromised patients.
结局指标
主要结局
Diagnosis of Spontaneous Bacterial Peritonitis- Correlation Between Mansoura Scoring System Vs Ascitic Fluid Analysis: Yes/no
时间窗: At 2 years
次要结局
- In-hospital Mortality During Course of Stay: Yes/no(At 2 years)
- Development of Acute Kidney Injury: Yes/no(At 2 years)
研究者
Kunal Agarwal
Kasturba Medical College, Manipal