TCTR20181119005Completed未知
Effects of inhaled essential oils on central nervous system, autonomic nervous system, emotional states and reaction time
Trial Snapshot
- Phase
- 未知
- Status
- Completed
- Sponsor
- Chulalongkorn university
- Enrollment
- 72
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 Years to 25 Years (—)
- Sex
- All
Inclusion Criteria
- •1. Male or female age between 18 and 25 years
- •2. Participants are right-handed that is confirmed by Edinburge Handedness Inventory test (83).
- •3. Participants have normal sense of smell that is confirmed by “n- butyl alcohol method test†before the experiment. This test measures the lowest concentration of a stimulus that can be distinguished between n-butyl alcohol and water. The normal participant can separate two odors at concentration lower than Step 6 (5.48×10-3v/v) of n- butyl alcohol in water (84-85).
- •4. Participants have no upper respiratory diseases, otorhinolaryngological infection, neurological diseases, hypertension or cardiovascular disease and physical conditions that may affect the sense of smell.
- •5. Participants have no history of neurological illness, epilepsy or loss of consciousness longer than 30 minutes.
- •6. Not taking CNS medication or presently taking recreational drugs
- •7. Normal blood pressure (systolic should not be higher than 140 mmHg,
- •diastolic not be higher than 90 mmHg)
- •8. Heart rate normal rhythm (should not be higher than 90)
- •9. Body mass index 18.5 †22.9 Kg/M2
- •10. Non †smoker
- •11. Each potential participant of will be asked to inhale the mixture of sweet almond oil and selected essential oil to fill out the pleasantness from “Odour familiarity five-point Likert scaleâ€. Only the potential participants who indicated oil pleasantness within the target level range of 2-4 will be recruited as participants.
Exclusion Criteria
- •1. Female who are presently menstruating
- •2. Have drowsiness before or during experiments experiment
- •3. Taking caffeine or alcohol for two hours before the test
- •4. Have abnormal brain wave which is detected by electroencephalogram
- •5. Participants who are allergic to essential oils will be excluded from the experiment
Investigators
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