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Clinical Trials/NCT06467474
NCT06467474
Recruiting
Not Applicable

Psychoeducation for Major Depressive Disorder: Development and Evaluation of Effectiveness

Ricardo Alberto Moreno, M.D., Ph.D.1 site in 1 country338 target enrollmentMarch 1, 2024

Overview

Phase
Not Applicable
Intervention
PEG-D program
Conditions
Major Depressive Disorder (MDD
Sponsor
Ricardo Alberto Moreno, M.D., Ph.D.
Enrollment
338
Locations
1
Primary Endpoint
Knowledge level
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The study aims to investigate the efficacy of a psychoeducational program as an adjunctive treatment for depression. The study will involve 338 patients diagnosed with Major Depressive Disorder (MDD) of moderate severity. Participants will be randomly assigned to receive either Treatment as usual (TAU) alone or TAU plus the psychoeducational program. The program consists of six weekly group sessions covering information and techniques for coping with depression. Primary outcomes include a reduction in depressive symptoms measured by the Beck Depression Inventory-II (BDI-II) and increased knowledge of depression. Secondary outcomes include improvements in functionality and quality of life. The study aims to provide insights into the effectiveness of psychoeducation in improving outcomes for individuals with depression

Registry
clinicaltrials.gov
Start Date
March 1, 2024
End Date
December 1, 2026
Last Updated
last year
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Ricardo Alberto Moreno, M.D., Ph.D.
Responsible Party
Sponsor Investigator
Principal Investigator

Ricardo Alberto Moreno, M.D., Ph.D.

PhD

University of Sao Paulo

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Arms & Interventions

Clinical Group

Participants will receive treatment as usual (TAU) associated with the psychoeducational program.

Intervention: PEG-D program

Clinical Group

Participants will receive treatment as usual (TAU) associated with the psychoeducational program.

Intervention: TAU

Control Group

The usual treatment will consist of outpatient follow-up for a period of twelve months.

Intervention: TAU

Outcomes

Primary Outcomes

Knowledge level

Time Frame: Time: baseline, post 6 weeks and 12 months.

Learning quiz: Comprising of open and closed questions questions, it was designed to evaluate participants' level of knowledge regarding depression

Depressive levels

Time Frame: Baseline, post 6 weeks, 3, 6 and 12 months.

Beck Depression Inventory-BDI-II. It consists of 21 items and measures the intensity of depression in the last 14 days. The instrument has 21 items, and the higher the score, the greater the intensity of depression.

Secondary Outcomes

  • Depressive Thoughts(Baseline, post 6 weeks, 3, 6 and 12 months)
  • Avoidance behaviors(Baseline, post 6 weeks, 3, 6 and 12 months.)
  • Functionality(Baseline, post 6 weeks, 3, 6 and 12 months.)

Study Sites (1)

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