Prediction of Intraoperative Blood Loss and Postoperative Recovery by Liver Stiffness Measurement (Fibroscan®) in Right Hepatectomy

Not Applicable

Completed

• Conditions: Liver Malignancy
• Interventions: Other: preoperative liver stiffness measurement

• Registration Number: NCT01483859
• Lead Sponsor: Yonsei University

Brief Summary

Liver stiffness measurement (LSM) using Fibroscan®(EchoSens, Paris, France) is a newly introduced noninvasive tool that generates an elastic wave using a vibrator applied to the thoracic wall at the level of the right lobe of the liver and measures the prolongation velocity of the wave, which is directly associated with liver stiffness (LS). Although recent advances in surgical techniques and perioperative management have made with established perioperative management have now made it possible to perform hepatectomies as a safe procedure with minimum mortality, the possibility of massive blood loss and resultant transfusion during hepatectomy still exist. The objective of this research was to identify the role of liver stiffness measurement for the prediction of intraoperative blood loss and postoperative recovery after elective right hepatectomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-09
• Study First Submitted: 2011-11-24
• Study First Submitted QC: 2011-11-29
• Primary Completion: 2011-12
• Study First Posted: 2011-12-01
• Study Completion: 2012-12
• Status Verified: 2015-07
• Last Update Submitted: 2015-07-14
• Last Update Posted: 2015-07-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 45

Inclusion Criteria

• patients undergoing right hepatectomy between August 2007 and July 2011

Exclusion Criteria

• patients undergoing right hepatectomy without preoperative liver stiffness measurement

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
right hepatectomy with preoperative LSM	preoperative liver stiffness measurement	patients undergoing right hepatectomy with preoperative LSM between August 2007 and July 2011

Primary Outcome Measures

Name	Time	Method
The correlation between the value of liver stiffness measurement and intraoperative blood loss during right hepatectomy	Participants will be followed for perioperative period, approximate 6 weeks through chart review.	The investigators will investigate the value of liver stiffness measurement and intraoperative blood loss during right hepatectomy through chart review. The investigators will analyze the correlation between the value of liver stiffness measurement and intraoperative blood loss during right hepatectomy

Trial Locations

Locations (1)

Severance Hospital; 🇰🇷 Seoul, Korea, Republic of