Effects of atorvastatin on diabetic nephropathy
Phase 2
- Conditions
- Diabetic nephropathy.Insulin-dependent diabetes mellitus with renal complications
- Registration Number
- IRCT2016100918946N4
- Lead Sponsor
- Vice chancellor for research, Tabriz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 42
Inclusion Criteria
Patients between 20 to 65 years old; patients with type 2 diabetes mellitus; history of gestational diabetes mellitus; proteinuria levels lower than 3 g/d (nephrotic range); estimated glomerular filtration rate more than 30 mL/min/1.73m2
Exclusion criteria: use of fibrates, statins antagonists, aspirin, allopurinol, ß-blockers, pentoxifylline, fish oil, other antioxidant drugs consumption in past 6 months; active smoking; active coronary artery disease in the previous 6 months; diabetic foot; hepatitis; poorly controlled diabetes (Hb-A1c more than 7.5%)
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ipid profile. Timepoint: Before intervention, 90 days after intervention initiation. Method of measurement: Blood samlple.;Serum creatinine. Timepoint: Before intervention, 90 days after intervention initiation. Method of measurement: Blood samlple.;Serum uric acid. Timepoint: Before intervention, 90 days after intervention initiation. Method of measurement: Blood samlple.;Urine Protein. Timepoint: Before intervention, 90 days after intervention initiation. Method of measurement: Blood samlple.
- Secondary Outcome Measures
Name Time Method