Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer: Concordance Study
Completed
- Conditions
- Breast Cancer
- Registration Number
- NCT00858585
- Lead Sponsor
- University of Michigan Rogel Cancer Center
- Brief Summary
This study will examine genes in three different tissues and look for similarities and differences between normal cells and cancer cells. The tissues to be studies come from blood, lymph node and cancer.
- Detailed Description
Subjects will be given an informed consent to read and sign The medical chart will be reviewed for diagnosis and treatment history Blood (about 4 tablespoons) will be drawn at a clinically available time. The lymph node and breast tumor tissue in the University of Michigan pathology repository will be used for research purposes
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 149
Inclusion Criteria
- Age at least 18 years of age
- Able to read and sign the informed consent
- Able to provide specimens: one blood draw for white blood cells, provide permission to use tissue already collected.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Single nucleotide polymorphisms time-independent Determine single nucleotide polymorphism concordances between the three DNA specimen sources
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Michigan
🇺🇸Ann Arbor, Michigan, United States