The compression of Misoprostol effect with and without Letrozole in first trimester abortion: A randomized clinical trial study
Phase 2
- Conditions
- Termination of pregnancy in the first trimester.Termination of pregnancy, fetus and newborn
- Registration Number
- IRCT201412111760N37
- Lead Sponsor
- Vice Chancellor for Research and Technology, Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 140
Inclusion Criteria
Following 12 weeks of pregnancy; Reason for termination of pregnancy, such as missed abortion; Pregnancy NULL; Therapeutic abortion legal authorization and consent of patients
Exclusion criteria:
Pain and bleeding; Drug sensitivity to misoprostol; Severe anemia; Coagulopathy or taking anticoagulants; Active liver disease; Cardiovascular disease and uncontrolled seizures; Adrenal disease, or a history of corticosteroid use
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Abortion. Timepoint: The start of the intervention up to 24. Method of measurement: Ultrasound.;Time between medication abortion. Timepoint: The start of the intervention up to 24. Method of measurement: Ultrasound.;The need for curettage. Timepoint: Seven days after abortion. Method of measurement: Clinical.
- Secondary Outcome Measures
Name Time Method Side effects. Timepoint: Intervention to 24 hours after administration. Method of measurement: Clinical.