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High-Voltage Pulsed Radiofrequency of the Lumbar Dorsal Root Ganglion for the Treatment of Chronic Lumbar Radicular and Neuropathic Pain; A Prospective, Doble-blinded and Randomized Controlled Trial

Not Applicable
Recruiting
Conditions
Pulsed Radiofrequency
Lumbar Radiculopathy
Interventions
Procedure: Radiofrequency
Registration Number
NCT06264297
Lead Sponsor
Consorci Sanitari de Terrassa
Brief Summary

The management of chronic lumbar radicular and neuropathic pain is complex and the treatment success rates are low. Pulsed radiofrequency (PRF) has been described in these cases. In order to determine whether high-voltage PRF show better results than PRF a prospective, doble-blinded and randomized study is conducted in patients with chronic lumbar radicular and neuropathic pain.

Detailed Description

Not available

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
98
Inclusion Criteria
  • Patients over 18 years of age.
  • Unilateral pain radiating to the lower extremity (with or without lumbar pain), which clinically corresponds to the path of the corresponding dermatomes.
  • Correlation between clinical symptoms and lesion observed by magnetic resonance imaging (MRI).
  • Radicular syndrome of three months or more of evolution.
  • Normal or pathological electromyogram (EMG).
  • Pain with neuropathic characteristics confirmed by the DN4 neuropathic pain questionnaire.
  • Patients with a previous positive block diagnosis.
  • Patients who have signed the informed consent document.
Exclusion Criteria
  • Patients under 18 years of age.
  • Patients with non-radicular low back pain.
  • MRI not consistent with the patient's symptoms.
  • Patients with peripheral neuropathy of the lower extremities.
  • Patients with a history or current diagnosis of serious mental disorder.
  • Patients with moderate or severe cognitive impairment, or evidence of acute or subacute confusional syndrome.
  • Infection at the puncture site.
  • Coagulation disorders.
  • Pregnant patients.
  • Patients who refuse to sign the informed consent document.
  • Patients allergic to radiological contrast.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
GROUP IIRadiofrequencyRFP on the affected level or levels will be carried out during three cycles of 120 s, limited to a temperature of 42° and a voltage of 65V
GROUP IRadiofrequencyRFP on the affected level or levels will be carried out during three cycles of 120 s, limited to a temperature of 42° and a voltage of 45V
Primary Outcome Measures
NameTimeMethod
OSWESTRY LOW BACK DISABILITY QUESTIONNAIREFrom enrollment to the end of treatment at 6 months

this questionnaire has been designed to give us information as to how your back pain has affected your ability to manage everyday life

Secondary Outcome Measures
NameTimeMethod
patient global impression of improvement (pgi-i) scoreFrom enrollment to the end of treatment at 6 months

is a transition scale that is a single question asking the patient to rate their urinary tract condition now, as compared with how it was prior to before beginning treatment

DN4 - QUESTIONNAIREFrom enrollment to the end of treatment at 6 months

DN4 - QUESTIONNAIRE To estimate the probability of neuropathic pain, please answer yes or no for each item of the following four questions.

Visual Numeric ScaleFrom enrollment to the end of treatment at 6 months

ranging from 0 to 10 was used to measure pain intensity

Categorical scaleFrom enrollment to the end of treatment at 6 months

uses adjectives, such as "mild," "moderate," "severe," and excruciating," to describe pain levels.

Trial Locations

Locations (1)

Consorci Sanitari de Terrassa

🇪🇸

Terrassa, Barcelona, Spain

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