NCT04448535CompletedNot Applicable
Effects of Ginkgo (Gingko Biloba) on Retinal and Choroidal Ocular Tissue
State University of New York College of Optometry1 site in 1 country20 target enrollmentStarted: January 1, 2021Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- ocular blood flow
Study Overview
Brief Summary
The purpose of this study is to understand the effect of Ginkgo Biloba oral supplements on retinal and choroidal ocular tissue.
Detailed Description
The study objectives are to:
1. assess the changes from pre- to post- oral supplementation on retinal and choroidal thickness and blood flow, retinal oxygen saturation, ocular perfusion pressure, and retinal function
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 20 Years to 55 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Aged between 20 - 55 years, inclusive
- •Good general and ocular health
- •Corrected visual acuity of 20/40 or better
- •No gingko biloba supplementation within the last 3 months
Exclusion Criteria
- •All significant ocular and any systemic disorders considered likely to affect the systemic or ocular vasculature
- •History of ocular surgery, including refractive surgery
- •Use of ocular medications
- •Conditions where ginkgo supplementation is contraindicated
- •Any eye or systemic disease that affect vision or refractive error
- •Current smokers
- •Subjects who are pregnant, breastfeeding, or planning conception
Outcomes
Primary Outcomes
ocular blood flow
Time Frame: 4 weeks
ocular blood flow measured with doppler ultrasound
Secondary Outcomes
No secondary outcomes reported
Investigators
Alexandra Benavente
Associate Clinical Professor
State University of New York College of Optometry
Study Sites (1)
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