The Effect of Allergen Immunotherapy on Exhaled Nitric Oxide in Adult Patients With Asthma and Allergic Rhinitis

Completed

• Conditions: Allergic Asthma; Allergic Rhinitis
• Interventions: Biological: Allergen immunotherapy

• Registration Number: NCT01318954
• Lead Sponsor: Rohr and Columbo Asthma, Allergy and Immunology Specialists, P.C.

Brief Summary

This study will evaluate whether exhaled nitric oxide levels are affected by allergen immunotherapy ("allergy shots"). The investigators' hypothesis is that successful allergen immunotherapy may be accompanied by decreased exhaled nitric oxide levels.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Study First Submitted: 2009-09-28
• Study First Submitted QC: 2011-03-17
• Study First Posted: 2011-03-21
• Primary Completion: 2011-06
• Study Completion: 2011-06
• Status Verified: 2015-10
• Last Update Submitted: 2015-10-28
• Last Update Posted: 2015-10-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• Subjects over 18 years old with allergic asthma and/or allergic rhinitis who are beginning allergen desensitization

Exclusion Criteria

• Smokers
• Subjects of dimished capacity

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Subjects on allergen immunotherapy	Allergen immunotherapy	Measurements of Nitric Oxide by NIOX MINO. This device is now FDA approved.

Primary Outcome Measures

Name	Time	Method
Effect of allergen immunotherapy on exhaled nitric oxide	One year

Trial Locations

Locations (1)

Rohr and Columbo Asthma, Allergy and Immunology Specialists, P.C.; 🇺🇸 Bryn Mawr, Pennsylvania, United States