To assess the efficacy of Echocardiographic parameter and carotid artery ultrasonosonography parameter to predict which patient need intravenous fluid in ICU

Completed

• Conditions: ICU patients on mechanical ventilation

• Registration Number: CTRI/2017/11/010434
• Lead Sponsor: AIIMS

Brief Summary

We did a prospective parallel group observational studyto assess efficacy of delta CA-VTI in predicting fluid responsiveness and itscorrelation with delta LVOT-VTI in critically patients on mechanicalventilation in sepsis, septic shock and those not in sepsis in a mixedmedical-surgical ICU.

To conclude, CA-VTI can be a useful dynamic variable toassess fluid responsiveness in critically ill patients on mechanicalventilation in sepsis and those not in sepsis and it correlates well withsimilar changes in LVOT-VTI and stroke volume in these patient population.However, in the more important subset of patient population with septic shock,usefulness of CA-VTI remains questionable. Further study with larger samplesize requires to be done to address this issue.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-04-01
• Study Completion: 2017-03-31
• Last Update Posted: 2017-06-11

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

mechanically ventilated adult patients (aged between 18-65 years.

Exclusion Criteria

• BMI>30 Kg/m2.
• Patients in whom PLR test cannot be performed (eg.raised ICP, intracranial space occupying lesions).
• Patients with valvular heart diseases.
• Patients with cardiomyopathy.
• Patients having carotid artery stenosis.
• Patients with pelvic and lower limb fractures.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Correlation of change in-left ventricular outflow tract velocity time integral (LVOT-VTI) and change in carotid artery velocity time integral (CA-VTI)	at the time of echocardiography - i.e., at the time of recruitment

Secondary Outcome Measures

Name	Time	Method
Correlation of delta LVOT VTI, delta SV and delta CA –VTI	And

Trial Locations

Locations (1)

All India Institute of Medical Sciences New Delhi; 🇮🇳 South, DELHI, India

All India Institute of Medical Sciences New Delhi

🇮🇳South, DELHI, India

Dalim Kumar Baidya

Principal investigator

9868398013

dalimkumar.ab8@gmail.com