NCT05401422Unknown不适用
Efficacy and Safety of Combining Doxycycline With Pulsed Dye Laser Versus Topical Brimonidine 0.33% in the Treatment of Erythematotelangiectatic Rosacea: a Comparative Clinical and Dermoscopic Study
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 45
- 主要终点
- Clinical erythema assessment scale
研究概览
简要总结
Rosacea is a chronic and relapsing inflammatory cutaneous disorder with highly variable prevalence worldwide.
详细描述
In our study, we will compare the safety, efficacy, and adverse effects of low-dose oral doxycycline alone versus combined with pulsed dye laser or topical brimonidine in treating erythematotelangiectatic rosacea in an attempt to build a treatment strategy in a disease with complex pathogenesis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient with current erythematotelangiectatic rosacea
排除标准
- •Pregnant females. 2-Patients on systemic steroids. 3-Patients complaining of other dermatological disorders mainly photosensitive cutaneous disorder.
- •4- Patients receiving any systemic treatment including retinoids for the previous 1 month or any topical treatment for the previous 2 weeks or any laser sessions for the previous 3months for erythematotelangiectatic rosacea at least.
结局指标
主要结局
Clinical erythema assessment scale
时间窗: 3 months
clinical scale
次要结局
- Thickness of capillaries by dermoscope(3 months)
研究者
相似试验
终止
2 期
Doxycycline for the Treatment of Cutaneous T-Cell LymphomaCutaneous T-cell LymphomaMycosis FungoidesSezary SyndromeNCT02341209Rochester General Hospital1
已完成
不适用
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled TrialRheumatoid ArthritisNCT03194204Assiut University160
已完成
不适用
Doxycycline in Therapy of Erythema MigransLyme BorreliosisNCT01475708University Medical Centre Ljubljana400
已完成
不适用
Doxycycline and dexamethasone as effective topical treatments for blepharitisEye DiseasesOther inflammation of eyelidBlepharitisISRCTN99872501Puente Genil Hospital (Hospital de Alta Resolución de Puente Genil) (Spain)25
已完成
2 期
Safety, Efficacy and Pharmacokinetics of Rifaximin in Patients With Moderate-to-severe Papulopustular RosaceaPapulopustular RosaceaNCT05150587Alfasigma S.p.A.216