Prospective Observational ICU Trial in Critical Ill COVID-19 Patients (POINT-C) Cardiovascular Risk and the Effects on Myocardial Events in Critical Ill COVID-19 Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- ICU CV risk and Biomarker (e.g. Troponin)
研究概览
简要总结
The aim of our study is to observe the intensive care course in 30-50 COVID-19 patients with regard to cardiovascular risk factors and biomarkers.
The primary objective of this study is to investigate the cardiovascular risk and its impact on cardiovascular complications in COVID-19 patients in intensive care units.
This study is designed to investigate correlations and to investigate factors influencing the course of the new viral disease COVID-19 in intensive care. Previous scientific findings are still rare due to the relevance of the disease, therefore this study is also explorative and not exclusively based on a hypothesis.
The cardiovascular risk will be assessed upon admission to the intensive care unit and subsequently the course of biomarkers (see below) will be analysed in a cohort study (no, low and high cardiovascular risk).
详细描述
In this prospective observational study the course of 30-50 intensive care patients of the University Hospital of Graz is analysed.
It is not possible to give an exact number of cases, because it is not possible to estimate exactly how many COVID-19 patients will be admitted to the listed intensive care units in Graz. Recruitment will start when approved from the ethical board and end in June, 2020.
Inclusion criteria
- Admission on an isolation unit - intensive care unit of the University Clinic of Graz
- Detection of a SARS - CoV-2 infection by PCR (tracheal or pharyngeal secretion) or CT examination (with consecutive PCR confirmation)
- male and female sex
- subordinated declaration of consent if possible*
- respiratory insufficiency with indication for non-invasive or invasive ventilation during admission to an intensive care unit
Informed consent
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Admission on an isolation unit - intensive care unit of the LKH Univ. Klinikum Graz
- •Detection of a SARS - CoV-2 infection by PCR (tracheal or pharyngeal secretion) or CT examination (with subsequent PCR detection)
- •male and female sex
- •subordinated declaration of consent if possible if applicable
- •respiratory insufficiency with indication for non-invasive or invasive ventilation
排除标准
- •if the inclusion criteria are not met
结局指标
主要结局
ICU CV risk and Biomarker (e.g. Troponin)
时间窗: through study completion, up to 4 weeks
Troponin courses in the intensive care unit are analyzed in consideration of the respective cardiovascular risk.
次要结局
- CV risk and Outcome during ICU stay(through study completion, up to 4 weeks)
研究者
Martin Rief
Dr.
Medical University of Graz