Effects of mirtazapine on serum levels of histamin and serotoni
Phase 3
- Conditions
- Chronic kidney disease.Chronic kidney disease (CKD)
- Registration Number
- IRCT20150629022965N18
- Lead Sponsor
- Hamedan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
aged above 18
diagnosis of end stage renal disease
receiving dialysis 3 times a week
no history of dermatological disorder which result in feeling itch
no history allergen medications or foods
no history of receiving medication which relieve itch
presence of moderate, severe and very severe pruritus
Exclusion Criteria
pregnancy or lactation
presence of liver failure
presence of any psychiatric disorder
Hyperphosphatemia
diabetic neuropathy
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum level of histamine. Timepoint: at baseline and 14 days later. Method of measurement: ELISA kit.;Serum level of serotonin. Timepoint: at baseline and 14 days later. Method of measurement: ELISA kit.
- Secondary Outcome Measures
Name Time Method