Knee and Hip OsteoArthritis Long Term Assessment. Prevalence, Natural History, Prognosis Factor, Quality of Life, Health Care Consumption and Social Consequences of Symptomatic Knee and Hip Osteoarthritis in France
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 878
- Locations
- 6
- Primary Endpoint
- Quality of life, patient reported outcome measures
Study Overview
Brief Summary
The aim of the project is to assemble and to follow on a 10-year period a nationwide representative sample of lower limb OA patients.
General objectives: To document the natural history and to identify predictive factors of the evolution and consequences of hip and knee OA in terms of pain, functional disability, structural damage, quality of life, autonomy, medical and health care use and cost of disease.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Masking
- None
Eligibility Criteria
- Ages
- 40 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •male and female aged between 40 and 75 years
- •symptomatic hip or knee, uni or bilateral OA with clinical diagnosis confirmed by a medical physician and satisfying ACR classification criteria
- •Representative of prevalent cases in France at the cohort set-up time
Exclusion Criteria
- •presence of hip or knee joint replacement surgery
- •comorbidities severe enough to affect quality of life significantly or likely to induce a high health care consumption independently of OA
- •an history of osteotomy
- •Patello-femoral osteoarthritis without tibio-femoral osteoarthritis
- •Other joint diseases of the target joints
- •adult under legal protection or not able to consent
Arms & Interventions
Study specific procedure
X-rays, biological samples and medical information about osteoarthritis
Intervention: X-rays (Procedure)
Study specific procedure
X-rays, biological samples and medical information about osteoarthritis
Intervention: biological samples (Biological)
Study specific procedure
X-rays, biological samples and medical information about osteoarthritis
Intervention: medical information about osteoarthritis (Other)
Outcomes
Primary Outcomes
Quality of life, patient reported outcome measures
Time Frame: every year, up to 10 years
Secondary Outcomes
- health care consumption(every year, up to 10 years)