Validation of Bioelectrical Impedance Vector Analysis for Nutritional Assessment in Patients With Cirrhosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Liver Cirrhosis
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
- Enrollment
- 250
- Locations
- 1
- Primary Endpoint
- Changes in nutritional status
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
Despite the importance of nutritional status in patient's outcome, there is no gold standard for nutritional assessment. Traditional techniques used in healthy subjects to assess nutritional status cannot be used in cirrhotic patients due especially to ascites and peripheral edema, and altered rates of biochemical markers due to liver failure.
Bioelectrical impedance vector analysis has emerged as a useful method to assess body composition and nutritional status especially in patients at the extremes of body weight (fluid overload, excess of adipose tissue, etc.).
With previous results from our research group, BIVA showed to be useful for evaluating cirrhotic patients.
The aim of this study is to validate our previous results and validate BIVA for nutritional assessment in patients with liver cirrhosis
Investigators
ALDO TORRE DELGADILLO
M.D., M.Sc.
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Eligibility Criteria
Inclusion Criteria
- •Diagnose of liver cirrhosis by two or more of the following criteria:
- •Albumin \< 3.4 g/dL
- •INR ≥ 1.3
- •Total bilirubin ≥ 2 mg/dL
- •Portal hypertension (esophageal varices, splenomegaly, ascites, etc.)
- •Liver biopsy
- •Ambulatory patients
Exclusion Criteria
- •Personal history of surgery in the last four weeks
- •Thyroid disorders without replacement therapy
- •Pregnancy
- •Active alcoholism with alcohol ingest in the previous 6 months.
- •Acute or chronic renal failure
- •Hepatic or renal transplant
Outcomes
Primary Outcomes
Changes in nutritional status
Time Frame: At the time of inclusion, every six months up to 36 months
It will be assessed by bioelectrical impedance vector analysis