NL-OMON37749已完成不适用
Residual effects of Cushing*s syndrome after long term remission: Impact on adipose tissue, insulin resistance, exercise intolerance and increased risk of cardiovascular disease. - Residual effects of Cushing*s syndrome
niversitair Medisch Centrum Sint Radboud0 个研究点目标入组 40 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Subjects should be over 18 years old with the ability to read and comprehend the Dutch language
- •- Patients should be successfully cured for at least five years. Current remission should be confirmed by a recent 1mg dexamethasone suppression test
排除标准
- •- GH deficiency (This should be ruled out by an insulin tolerance test or an arginine/GHRH test) unless GH is properly supplemented (IGF-1 * 2)
- •- Serious co-morbidity (i.e. terminal malignancy, serious psychiatric pathology)
- •- Pregnancy
- •- Known diabetes mellitus
- •- Use of medication interfering with the cardiovascular system (ACE inhibitors, calcium antagonists, angiotensin II receptor antagonists) or adiponectins (thiazolidinediones)
- •- Severe cardiopulmonary disease as stated in the 2001 American heart association and 2002 American college of cardiology/American heart association guidelines
- •- Orthopedic and/or neurological diseases that impair exercise
研究者
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