Collection of Blood and Bone Marrow From Patients With Aplastic Anemia for Analysis of Adhesion Molecules, Chemokines and Their Receptors

Shandong University1 site in 1 countryFebruary 2009

ConditionsAplastic Anemia Healthy

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Aplastic Anemia
Sponsor: Shandong University
Locations: 1
Primary Endpoint: hematologic response
Status: Withdrawn
Last Updated: 10 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study is designed to collect bone marrow and/or peripheral blood cells and plasma, for the analysis of adhesion molecules, chemokines and their receptors from newly-diagnosed aplastic anemia patients, and patients treated with antithymocyte globulin plus cyclosporine

Registry

clinicaltrials.gov

Start Date

February 2009

End Date

November 2012

Last Updated

10 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Shandong University

Responsible Party

Principal Investigator

Ming Hou

Director

Shandong University

Eligibility Criteria

Inclusion Criteria

•patients who fulfilled entry criteria of acquired aplastic anemia age range 16-70 years

Exclusion Criteria

•Patients complicated with diabetes, tumor, pregnancy, active infection, or connective tissue diseases, such as systemic lupus erythematosus.

Outcomes

Primary Outcomes

hematologic response

Time Frame: 6 months following antithymocyte globulin plus cyclosporine treatment

hematologic response at 6 months following antithymocyte globulin plus cyclosporine treatment, defined as no longer meeting the criteria for severe aplastic anemia