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A Study of YM178 in Patients With Symptomatic Overactive Bladder

Phase 2
Completed
Conditions
Urinary Bladder, Overactive
Interventions
Drug: Placebo
Registration Number
NCT00527033
Lead Sponsor
Astellas Pharma Inc
Brief Summary

Examine which dose of YM178 is the best in terms of efficacy, safety and tolerability compared to placebo

Detailed Description

To investigate the dose-response relationship of YM178 in terms of efficacy, safety and tolerability, and also the superiority of YM178 over placebo.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
842
Inclusion Criteria
  • Patients over 20 years suffering from overactive bladder
Exclusion Criteria
  • Pregnant and breastfeeding women
  • Any clinically significant abnormal conditions which in the opinion of the investigator makes the patient unsuitable for the study

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1YM178Oral
2YM178Oral
3YM178Oral
4PlaceboOral
Primary Outcome Measures
NameTimeMethod
Overactive bladder symptoms12 weeks
Secondary Outcome Measures
NameTimeMethod
Overactive bladder symptoms (QOL)12 weeks
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