addition of two different drugs Buprenorphine or Dexamethasone to Levobupivacaine in TAP block may or may not provide better pain control in inguinal hernia repair

Not yet recruiting

• Conditions: ASA grade 1 and 2

• Registration Number: CTRI/2017/10/010081
• Lead Sponsor: Dr S N medical collage and attached hospital Jodhpur

Brief Summary

This is a prospective randomized double blind study. The institutional ethical committee clearance obtained and informed consent would be taken from patient. The total 93 patients of age between 18-60 years, ASA Grade 1 and 2 undergoing unilateral inguinal hernioplasty would be randomly divided in three groups of 31 each. After surgery under spinal anaesthesia group L will receive 20ml 0.25% levobupivacaine + 1 ml NS, group LB will receive 20ml 0.25% levobupivacaine + 0.3mg buprenorphine and group LD will receive 20ml 0.25% levobupivacaine + 4mg dexamethasone, total 21ml in each ultrasound guided TAP block. Postoperatively we will record and compare the duration of analgesia, total rescue analgesic (tramadol) consumption and NRS pain score in first 24 hrs.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-10-16
• Last Update Posted: 2017-12-10

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 93

Inclusion Criteria

• Age group of 18 –60 years of both sex 2.
• ASA grade I and II 3.
• Weight 50-100 kg 4.
• Patients undergoing surgery for unilateral inguinal hernia repair.

Exclusion Criteria

• Patient’s or relative’s refusal 2.
• Known hypersensitivity to local anesthetics 3.
• Opioid addicts 4.
• Any chronic systemic illness 5.
• Bleeding diasthesis 6.
• Anatomical abnormality 7.
• Any infection at the regional site 8.
• Pregnant women 9.
• Pre existing peripheral neuropathy or neurological deficits.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To compare post operative pain score (NRS).	24 hours
Duration of analgesia.	24 hours
To compare post operative rescue analgesic (inj.tramadol) requirment.	24 hours

Secondary Outcome Measures

Name	Time	Method
•To compare the hemodynamic and respiratory parameters.	24 hours
•Patient’s satisfaction.	24 hours
•Any side effects or complications of study drugs and block.	24 hours

Trial Locations

Locations (1)

MDM hospital; 🇮🇳 Jodhpur, RAJASTHAN, India

MDM hospital

🇮🇳Jodhpur, RAJASTHAN, India

Dr Satya narayan seervi

Principal investigator

7737658824

drsatyanarayanseervi@gmail.com