Fesoterodine ameliorates the activity in frontal brain micturition area and the hypersensibility of bladder afferent nerves in patients with OAB symptoms. - Fesoterodine ameliorates frontal activity and OAB symptoms

eurology, Sakura Medical Center, Toho University0 个研究点目标入组 53 人开始时间: 2014年2月15日最近更新: 2023年10月17日

适应症

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•Subject who had a known disorder that damages a spinal cord (e.g., spinal cord injury, lumbar spondylosis, spina bifida etc.). Subjects with indwelling catheter or who require the clean intermittent catheterization(CIC) Subject who had a residual urine volume (sonographic) >100 mL, or a prostate size >30 ml at Visit 1. Subject who had a complication of lower urinary tract pathology potentially responsible for urgency or incontinence (e.g., bladder stone, interstitial cystitis, urothelial tumors etc.), clinically relevant bladder outlet obstruction (e.g., benign prostatic hypertrophy etc.) Subject who had an active urinary tract infection (UTI) as shown by the results of the urinalysis at Visit 1 or recurrent urinary tract infection defined as treatment for UTI >=3 times in the last year. Subject who was known to have polyuria (>3000 mL/24h). Subject who had been treated with OAB treatment agents, such as antimuscarinic drugs within 2 weeks prior to Visit 1. Subject who, in the opinion of the investigator, was not likely to complete the trial for whatever reason.

发起方

eurology, Sakura Medical Center, Toho University