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临床试验/NCT01686113
NCT01686113已完成不适用

Free Fatty Acids: Short Exposure Study

Purdue University2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2012年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
100
试验地点
2
主要终点
NEFA detection threshold

研究概览

简要总结

This study will examine whether or not short, daily exposures change a person's ability to detect free fatty acids in a solution by its taste. Repeated exposure should improve a person's ability to detect free fatty acids.

详细描述

The possibility that humans can taste non-esterified fatty acids (NEFA) - so-called fat taste - is a relatively new area of research. Previous work suggests that subjects require an average of between two and three testing sessions of approximately an hour each before they can reliably detect NEFA, and the average number of visits to get the lowest threshold is six. Streamlining this process is of great interest to researchers who wish to test many people as quickly as possible. Other taste qualities, including umami and sweet, have shown improvement in detection sensitivity in subjects that have undergone ten second exposures to these taste qualities for 10 days upon subsequent re-testing. We seek to determine if the same improvements can be seen with fat taste.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • good health
  • available for multiple testing visits

排除标准

  • have participated in a fat taste study in the past 6 months

结局指标

主要结局

NEFA detection threshold

时间窗: 10 days

次要结局

  • BMI(1 day)
  • Hunger(2 days)
  • Taste descriptor(10 days)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard Mattes

Distinguished Prof Foods and Nutrition

Purdue University

研究点 (2)

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