Skip to main content
Clinical Trials/NCT02123888
NCT02123888UnknownNot Applicable

Simultaneous Cone Beam Computed Tomography (CBCT) Acquisition During Arc Radiotherapy

Sally Falk2 sites in 1 country75 target enrollmentStarted: June 2011Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Sponsor
Sally Falk
Enrollment
75
Locations
2
Primary Endpoint
Equivalence of image quality

Study Overview

Brief Summary

The cone beam image is a part of the radiotherapy treatment machine and uses lower energy xrays as the head of the radiotherapy machine moves around the patient in a circle. This takes pictures that give 3-dimensional information, somewhat like a CT scan. These images are better at showing the position of the tumour and surrounding soft tissues than the standard xrays that were previously used. Cone Beam Imaging Technology is not new and has been used regularly at The Christie for many years. The standard cone beam scan is taken before the actual radiotherapy treatment or after the treatment has been delivered.

Volumetric Modulated Arc Therapy (VMAT or Arc Radiotherapy) is a novel method of delivering radiotherapy that involves the continuous movement of the radiotherapy treatment machine head around the patient and MLC during radiation. Arc radiotherapy has been clinically implemented at The Christie for prostate radiotherapy treatments and work is in progress for implementation in lung radiotherapy. The continuous gantry rotation inherent to VMAT delivery makes this simultaneous imaging possible, although there are concerns associated with the impact that this may have on patient dose and image quality.

The aim of this research is to assess whether the image quality of cone beam scans taken during treatment are as good as standard cone beam scans taken before or after treatment used to determine the accuracy of patient position and the tumour coverage by radiotherapy.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Equivalence of image quality

Time Frame: 12 months

To show equivalence of image quality from simultaneous CBCT acquisition during delivery of arc radiotherapy with that obtained from conventional CBCT acquisition in lung and prostate patients, as assessed by user-questionnaires.

Secondary Outcomes

  • Quantify impact on treatment times.(12 months)
  • Quantify inter-observer variation(12 months)

Investigators

Sponsor
Sally Falk
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Sally Falk

Clinical Trial Project Manager

The Christie NHS Foundation Trust

Study Sites (2)

Loading locations...

Similar Trials