Non-surgical Treatment of Knee Osteoarthritis - a Comparison of Effects in 2200 Patients

Completed

• Conditions: Knee Osteoarthritis
• Interventions: Drug: Paracetamol and nonsteroidal antiinflammatory drug (NSAID); Other: Physiotherapy; Drug: Cortisone Injection; Other: Others

• Registration Number: NCT02091830
• Lead Sponsor: Northern Orthopaedic Division, Denmark

Brief Summary

The purpose of this study is to assess whether radiographic osteoarthritis severity (OA; Kellgren-Lawrence scale) is associated with self-reported improvement in pain after non-surgical treatments (physiotherapy, pain killers, injection, other treatments).

The hypothesis is that radiographic OA severity is inversely associated with self-reported improvement.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01
• Study First Submitted: 2014-03-18
• Study First Submitted QC: 2014-03-18
• Study First Posted: 2014-03-19
• Primary Completion: 2014-07
• Study Completion: 2014-07
• Status Verified: 2015-10
• Last Update Submitted: 2015-10-16
• Last Update Posted: 2015-10-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2262

Inclusion Criteria

• Not eligible for at total knee arthroplasty

Exclusion Criteria

• Ipsilateral knee arthroplasty

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Non-surgical treatment	Paracetamol and nonsteroidal antiinflammatory drug (NSAID)	-
Non-surgical treatment	Physiotherapy	-
Non-surgical treatment	Cortisone Injection	-
Non-surgical treatment	Others	-

Primary Outcome Measures

Name	Time	Method
Self-reported improvement	2-5 years after consulting orthopedic surgeon	Assessed using the question: Has your pain improved? Response categories: pain free; better; unchanged; worse

Trial Locations

Locations (1)

Department of Orthopedic Surgery; 🇩🇰 Aalborg, Denmark