Prediction of outcomes and response to treatments with an ultrasensitive method for assessing intratumor epigenetic heterogeneity in colorectal cancer
Not Applicable
Completed
- Conditions
- Colorectal cancer
- Registration Number
- JPRN-UMIN000021191
- Lead Sponsor
- Juntendo University Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1.Patients do not meet the inclusion criteria 2.Patients without histologically confirmed cancer 3.Patients whom investigators consider to be ineligible
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The detection rates of epigenetic heterogeneity in primary tumor and plasma from colorectal cancer patients with Methylation-sensitive high resolution melt(MS-HRM).
- Secondary Outcome Measures
Name Time Method 1.To investigate the diffenrences in the detection rates between quantitative methylation specific PCR (qMSP) and MS-HRM 2.To investigate the correlations between epigenetic heterogeneity and gene expression in primary tumor from colorectal cancer patients