Multifaceted Intervention for Protection Against Cotton Dust Exposure Among Textile Workers

Not Applicable

Completed

• Conditions: Occupational Lung Disease; Occupational Diseases
• Interventions: Behavioral: Multifaceted intervention package

• Registration Number: NCT03738202
• Lead Sponsor: Aga Khan University

Brief Summary

Textile workers are exposed to various harmful substances during work, including cotton dust, which is the dust present in air during the handling or processing of cotton. Previous research found a link between cotton dust exposure and impaired respiratory health. This study will comprise of administration and workers' training regarding preventive measures for protection against respiratory illnesses. Workers will be provided free, disposable face masks and measures to reduce cotton dust exposure will be introduced at the textile mills. The study would then determine the effectiveness of this intervention on reduction in cotton dust levels in the mills, and improvement in respiratory health of workers. This study would help the cotton textile workers and managers reduce the health hazards of cotton dust exposure and also guide researchers from Pakistan and other low-resource countries towards developing relevant strategies for health protection of these workers.

Detailed Description

The textile, clothing and footwear sector provides employment to more than 60 million people worldwide, mostly in developing countries. Pakistan's textile industry accounts for 8.5% of the national GDP and employs around 40% of the industrial workforce. High burden of respiratory illnesses, including byssinosis and lung function decrements has been reported among cotton textile workers in developing countries and previous work undertaken by Dr Nafees found a high burden in Pakistan. Dr Nafees recently implemented an interventional study designed to improve workers' knowledge, attitude and practices and respiratory health, and reduce dust exposure at cotton textile mills through a multifaceted intervention (MultiTex pilot study). The preliminary findings from the pilot were helpful in improving the overall design and implementation of a larger and more definitive study (cluster randomised controlled trial). The aim of the trial would be to determine the effectiveness of a multifaceted interventional package for improvement in reducing dust levels at the cotton textile mills as well as improvement in respiratory health of textile workers.This study will add important context-specific knowledge regarding preventive strategies in cotton mills with policy implications for Pakistan and other developing countries.

Study Timeline

• Study First Submitted: 2018-11-08
• Study First Submitted QC: 2018-11-09
• Study First Posted: 2018-11-13
• Study Start: 2019-06-15
• Primary Completion: 2022-07-15
• Study Completion: 2022-07-15
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-03
• Last Update Posted: 2023-08-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 2031

Inclusion Criteria

• Inclusion criteria for textile mills:
• Mills from the formal sector will be included.
• Mills which have either spinning or weaving sections, or both.
• Mills that have at least 50-100 workers (primarily labourers/machine operators) in the spinning and weaving sections.
• Mills with a more stable working population will be preferred.
• Willingness of management to participate in planning and implementation of the study.
• Inclusion criteria for textile workers:
• Those ≥18 years and employed in the bale opening, blowing, carding, spinning, weaving and waste recycling sections (and related sub-sections).

Exclusion Criteria

• Textile workers from the wet-processing areas as well as support or administrative staff will be excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Intervention	Multifaceted intervention package	Multifaceted intervention package will be implemented at textile mills in the intervention arm.

Primary Outcome Measures

Name	Time	Method
Changes in cotton dust personal exposure levels expressed as mg/m3	24 months	Will be assessed through the use of IOM samplers
Changes in the prevalence of respiratory symptoms	24 months	Will be assessed through MRC respiratory questionnaire; symptoms include chest tightness, cough, phlegm, chronic bronchitis, wheezing and shortness of breath.
Changes in Forced Expiratory Volume in first second (FEV1) measured in in ml	24 months	Will be assessed through spirometry

Trial Locations

Locations (1)

Aga Khan University; 🇵🇰 Karachi, Pakistan