Effects of Pranayama on Fatigue Among Patients Undergoing Chemotherapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 25
- 试验地点
- 2
- 主要终点
- Feasibility
研究概览
简要总结
The purpose of this study is to determine the feasibility and efficacy of yoga breathing techniques to manage fatigue and other cancer-related side effects, in cancer patients undergoing chemotherapy.
详细描述
Fatigue is the most common complaint among cancer patients. This pilot study will evaluate the effects of pranayama (ancient yoga breathing techniques) on fatigue and quality of life among 30 patients undergoing chemotherapy, on an every 2, 3, or 4 week schedule, with a fatigue score of at least 4 on a scale of 0 (none) to 10 (most). Patients will be randomized to either pranayama or wait-list control. The pranayama group will learn and practice 3 breathing techniques on a daily basis. The study period will occur during 2 consecutive cycles of chemotherapy (cycle A and Cycle B), and the wait-list control patients will crossover to the treatment arm at the beginning of his/her Cycle B. Fatigue will be measured using the revised Piper Fatigue Scale along with quality of life measures. These study measures will be conducted at baseline, at the end of cycle A, and at the end of cycle B. We hypothesize that pranayama will improve clinical symptoms of fatigue and quality of life among patients undergoing chemotherapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A diagnosis of cancer that requires at least 2 further cycles of chemotherapy on an every 14, 21, or 28 day schedule
- •A score of at least 4/10 on a 0-10 (0-none, 10-most) visual analog scale for fatigue at the time of enrollment
- •Able to read, write and understand English
- •Karnofsky Performance Status greater than 60
- •Ability to give informed consent
排除标准
- •Severe COPD
- •Receiving chronic oxygen therapy
- •Congestive heart failure: NYHA class 3 or greater
- •Transfusion dependent anemia
- •Uncontrolled thyroid disease
- •Advance kidney disease requiring dialysis
- •Advance liver disease
- •More than three previous chemotherapy regimens
- •Current, ongoing yoga breathing practice
结局指标
主要结局
Feasibility
时间窗: Baseline and second cycle of chemotherapy
Feasibility will be evaluated based on recruitment, retention, completion of study classes and home practice, and completion of study measures
次要结局
- Cancer associated symptoms and quality of life(baseline and final cycle of chemotherapy)
研究者
Anand Dhruva
Assistant Clinical Professor
University of California, San Francisco