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The Efficacy of Group-based Unified Protocol (UP) Programme for Improving Sleep and Mental Health

Not Applicable
Conditions
Quality of Life
Insomnia
Depression, Anxiety
Interventions
Behavioral: Unified Protocol for mood disorders
Registration Number
NCT05394753
Lead Sponsor
The University of Hong Kong
Brief Summary

Common mental disorders can be disabling and lead to a large burden of disease. Unified Protocol for Transdiagnostic Treatment of Emotional Disorders was developed to address emotional disorders with evidence-based emotional-focused cognitive-behavioural techniques and is efficacious in reducing anxiety symptoms and depressive symptoms in adults. Previous research has demonstrated comparable effect of UP on reducing anxiety symptoms compared with the single-disorder protocol (SDP) for anxiety. Group-based UP was also implemented and tested. Given the fact that working populations are at a high risk of poor mental health, especially in light of the COVID pandemic with new unprecedented work situations and increased uncertainties, the present study aims to investigate the efficacy of Unified protocol on sleep and mental health in high-risk population.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
80
Inclusion Criteria
  • Working in local schools or education institutions
  • aged 18 or above
  • no severe or unstable mental health conditions at recruitment
  • no extensive prior training/practice with mindfulness
Exclusion Criteria
  • psychotic disorders, bipolar disorder, severe alcohol disorder and substance abuse, acute and high suicidal risk
  • currently receiving taking other psychosocial interventions

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Unified ProtocolUnified Protocol for mood disorders8-session group-based intervention
Primary Outcome Measures
NameTimeMethod
Change in Positive affectweek 1, week 5, week 9, 12 weeks after completion of intervention

Positive and Negative Affect Schedule (PANAS), 4 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change in Negative affectweek 1, week 5, week 9, 12 weeks after completion of intervention

Positive and Negative Affect Schedule (PANAS), 4 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change of insomnia symptomsweek 1, week 5, week 9, 12 weeks after completion of intervention

Insomnia symptoms are measured by Insomnia Severity Index (ISI). ISI is a 5-item self-rated scale. Possible scores range from 0 to 20, with higher scores indicating higher insomnia severity.

Secondary Outcome Measures
NameTimeMethod
Change of Sleep Diary Measure - Time in Bed (TIB)week 1, week 9, 12 weeks after completion of intervention

Daily sleep diary for consecutive seven days. Sleep parameter estimated by daily sleep diary: time in bed (TIB) in hours

Change of Sleep Diary Measure - Wake After Sleep Onset (WASO)week 1, week 9, 12 weeks after completion of intervention

Daily sleep diary for consecutive seven days. Sleep parameter estimated by daily sleep diary: wake after sleep onset (WASO) in mins

Change in Mindfulnessweek 1, week 9, 12 weeks after completion of intervention

Cognitive and Affective Mindfulness Scale-Revised (CAMS-R), 12 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change of clinically anxiety symptomsweek 1, week 5, week 9, 12 weeks after completion of intervention

General Anxiety Disorder-7 (GAD-7) consists of 7 self-report items designed to assess general anxiety symptoms. Higher scores indicate high level of anxiety.

Change in Objective Sleep Measures - Sleep Efficiency (SE)week 1, week 9, 12 weeks after completion of intervention

Actigraphic assessment for consecutive seven days. Sleep parameter estimated by wrist actigraphy: sleep efficiency (SE), which is calculated by total sleep time divided by total time in bed, %

Change in General Healthweek 1, week 5, week 9, 12 weeks after completion of intervention

General Health Questionnaire (GHQ), 12 items, 4-point Likert scale ranging from 1 (never) to 5 (always)

Change in Common humanityweek 1, week 9, 12weeks after completion of intervention

Common Humanity scale, 10 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change in Decenteringweek 1, week 9, 12 weeks after completion of intervention

Non Reactivity Subscale of Chinese Five Facet Mindfulness Questionnaire (FFMQ-C), 4 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change of subjective mental well-beingweek 1, week 5, week 9, 12 weeks after completion of intervention

The World Health Organisation- Five Well-Being Index (WHO-5) consists of 5 self-report items designed to measure subjective well-being. Higher scores indicate better well-being.

Change of quality of lifeweek 1, week 5, week 9, 12weeks after completion of intervention

WHOQOL-BREF, 26 items, 5-point Likert scale ranging from 1 (never/very bad/strongly disagree) to 5 (always/very good/strongly agree)

Change of Sleep Diary Measure - Sleep Efficiency (SE)week 1, week 9, 12 weeks after completion of intervention

Daily sleep diary for consecutive seven days. Sleep parameter estimated by daily sleep diary: sleep efficiency (SE), which is calculated by total sleep time divided by total time in bed, %

Change in Objective Sleep Measures - Total Sleep Time (TST)week 1, week 9, 12 weeks after completion of intervention

Actigraphic assessment for consecutive seven days. Sleep parameter estimated by wrist actigraphy: total sleep time (TST) in hours

Change in Self-compassionweek 1, week 9, 12 weeks after completion of intervention

Self-compassion scale, 6 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

TMSS-repairweek 1, week 9, 12 weeks after completion of intervention

Trait Meta-Mood Scale repair subscale, 6 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

RRSweek 1, week 5, week 9, 12 weeks after completion of intervention

Ruminative responsive scale, 22 items, 4-point Likert scale ranging from 1 (almost never) to 4 (almost always)

Change in Emotion Regulationweek 1, week 5, week 9,12 weeks after completion of intervention

Reappraisal subscale of Emotion Regulation Questionnaire (ERQ), 10 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change of pre-sleep arousalweek 1, week 9, 12 weeks after completion of intervention

Pre-Sleep Arousal Scale is a 16-item self-rated scale measuring pre-sleep arousal. There are two subscales on the cognitive and somatic manifestations of arousal, with eight items in each subscale (possibly scored from 8 to 40). In both cases, a higher score indicates higher pre-sleep arousal.

Change of sleep reactivityweek 1, week 9, 12 weeks after completion of intervention

Ford Insomnia Response to Stress Test (FIRST) consists of 9 items designed to measure sleep reactivity. Possible scores range from 9 to 36. A higher score indicates higher sleep activity.

Change of Sleep Diary Measure - Total Sleep Time (TST)week 1, week 9, 12 weeks after completion of intervention

Daily sleep diary for consecutive seven days. Sleep parameter estimated by daily sleep diary: total sleep time (TST) in hours

Change of Sleep Diary Measure - Sleep Onset Latency (SOL)week 1, week 9, 12 weeks after completion of intervention

Daily sleep diary for consecutive seven days. Sleep parameter estimated by daily sleep diary: sleep onset latency (SOL) in mins

Change in Objective Sleep Measures - Time in Bed (TIB)week 1, week 9, 12 weeks after completion of intervention

Actigraphic assessment for consecutive seven days. Sleep parameter estimated by wrist actigraphy: time in bed (TIB) in hours

Change of objective sleep measure (sleep onset latency, SOL)week 1, week 9, 12 weeks after completion of intervention

Actigraphic assessment for consecutive seven days. Sleep parameter estimated by wrist actigraphy: sleep onset latency (SOL) in mins

Change in Objective Sleep Measures - Wake After Sleep Onset (WASO)week 1, week 9, 12 weeks after completion of intervention

Actigraphic assessment for consecutive seven days. Sleep parameter estimated by wrist actigraphy: wake after sleep onset (WASO) in mins

Change in Stressweek 1, week 5, week 9, 12 weeks after completion of intervention

Perceived Stress Scale (PSS), 10 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change in Compassionweek 1, week 9, 12 weeks after completion of intervention

Compassion scale, 6 items, 5-point Likert scale ranging from 1 (never) to 5 (always)

Change of clinically depressive symptomsweek 1, week 5, week 9, 12 weeks after completion of intervention

Patient Health Questionnaire-9 (PHQ-9) consists of 9 self-report items designed to assess clinically significant depression. Higher scores indicate high level of depression.

Trial Locations

Locations (1)

Sleep Research Clinic and Laboratory, Department of Psychology, The University of Hong Kong

🇭🇰

Hong Kong, Hong Kong

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