Efficacy of Joshanda Mussaffi orally with local application of Tila versus Clotrimazole 1% lotion in Tinea Incognito–A Single Blind Randomized Controlled Trial.

This randomized, single-blind controlled clinical trial aims to evaluate the efficacy of Joshanda Mussaffi given orally along with the local application of Tila (Unani formulation) in comparison with topical Clotrimazole 1% lotion for the management of Tinea Incognito. Tinea Incognito is a dermatophytic infection modified by prior inappropriate corticosteroid use, often presenting with atypical features and delayed diagnosis.

A total of eligible patients fulfilling the inclusion and exclusion criteria will be randomly allocated into two groups. Group A will receive Joshanda Mussaffi orally with local application of Tila, while Group B will receive standard therapy with topical Clotrimazole 1% lotion. Sample size no 42.The treatment duration, follow-up schedule, and outcome assessment will be uniform for both groups.

The primary outcome will be the reduction in clinical severity based on signs and symptoms scoring. Secondary outcomes include improvement in pruritus, lesion size reduction, and mycological clearance confirmed by KOH microscopy. Safety assessment and adverse event monitoring will also be conducted throughout the study.

The study aims to scientifically validate the effectiveness and safety of traditional Unani treatment compared to standard antifungal therapy for Tinea Incognito.