EVALUATION OF RESPIRATORY MECHANICS AND FUNCTIONALITY IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Completed

• Conditions: Pulmonary Disease, Chronic Obstructive

• Registration Number: NCT03086590
• Lead Sponsor: Universidade Federal de Pernambuco

Brief Summary

To associate a lean mass, peripheral muscle strength, kinematic thoracic-abdominal, respiratory metabolic response, mobility and diaphragmatic thickness, verifying its relation with the obstruction level of COPD

Detailed Description

Individuals with COPD present restriction in their daily lives due to changes and bodily disorders promoted by the disease, such as changes in types of muscle fibers and chronic inflammatory process, causing a low level of physical activity and quality of life, besides being closely Related to the need for hospitalizations and increased mortality. A cross-sectional study with a convenience sample was performed at the Laboratory of Cardiopulmonary Physiotherapy of the Federal University of Pernambuco during the period from December 2016 to February 2018. As measurements of body composition were performed with a bio-balance scale, Evaluation of the peripheral muscle strength will be used the dynamometer, a load cell and electromyography, a kinematic thoracic-abdominal will be measured by optoelectronic plethysmography, a respiratory metabolic response will be verified during the 6-minute walk test using the gas analyzer, and for evaluation of mobility and diaphragmatic thickness are used on ultrasound associated with pneumotachograph.

Study Timeline

• Study Start: 2016-11-01
• Study First Submitted: 2017-03-09
• Study First Submitted QC: 2017-03-15
• Study First Posted: 2017-03-22
• Primary Completion: 2018-02-01
• Study Completion: 2018-03-01
• Status Verified: 2018-11
• Last Update Submitted: 2018-11-05
• Last Update Posted: 2018-11-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Young adults, adults and elderly subjects

Exclusion Criteria

• Others respiratory diseases;
• Heart diseases;
• Those who are in some previous training program or rehabilitation;

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oxygen uptake	Baseline	Consumption of oxygen during an effort.
Diaphragm thickness	Baseline	Defined as a corpulence of the diaphragm muscle
Fat-free mass	Baseline	Mass of the human body disregarding fat.
Quadriceps Force	Baseline	Quadriceps muscle strength measured during maximum voluntary contraction.
Handgrip strength	Baseline	Maximum voluntary manual holding force.
Total chest wall volume	Baseline	Total volume resulting from the sum of the volume of the pulmonary compartment of the costal, abdominal gradient of the costal and abdominal beds.
Diaphragm mobility	Baseline	It is the diaphragmatic movement from the end of the expiration until the end of the inspiration, being able to be realized in tidal volume or starting from the total pulmonary capacity.

Trial Locations

Locations (1)

Universidade Federal de Pernambuco; 🇧🇷 Recife, Pernambuco, Brazil