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Clinical Trials/NCT03086590
NCT03086590
Completed
Not Applicable

BODY COMPOSITION, PERIPHERAL MUSCULAR FORCE, KINEMATIC THORACIC-ABDOMINAL, VENTILATORY METABOLIC RESPONSE, DIAPHRAGM MOBILITY AND THICKNESS PREDICTION OF OBSTRUCTION LEVEL OF COPD?

Universidade Federal de Pernambuco1 site in 1 country20 target enrollmentNovember 1, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pulmonary Disease, Chronic Obstructive
Sponsor
Universidade Federal de Pernambuco
Enrollment
20
Locations
1
Primary Endpoint
Fat-free mass
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

To associate a lean mass, peripheral muscle strength, kinematic thoracic-abdominal, respiratory metabolic response, mobility and diaphragmatic thickness, verifying its relation with the obstruction level of COPD

Detailed Description

Individuals with COPD present restriction in their daily lives due to changes and bodily disorders promoted by the disease, such as changes in types of muscle fibers and chronic inflammatory process, causing a low level of physical activity and quality of life, besides being closely Related to the need for hospitalizations and increased mortality. A cross-sectional study with a convenience sample was performed at the Laboratory of Cardiopulmonary Physiotherapy of the Federal University of Pernambuco during the period from December 2016 to February 2018. As measurements of body composition were performed with a bio-balance scale, Evaluation of the peripheral muscle strength will be used the dynamometer, a load cell and electromyography, a kinematic thoracic-abdominal will be measured by optoelectronic plethysmography, a respiratory metabolic response will be verified during the 6-minute walk test using the gas analyzer, and for evaluation of mobility and diaphragmatic thickness are used on ultrasound associated with pneumotachograph.

Registry
clinicaltrials.gov
Start Date
November 1, 2016
End Date
March 1, 2018
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Rodrigo Viana Correia de Souza

Principal Investigator

Universidade Federal de Pernambuco

Eligibility Criteria

Inclusion Criteria

  • Young adults, adults and elderly subjects

Exclusion Criteria

  • Others respiratory diseases;
  • Heart diseases;
  • Those who are in some previous training program or rehabilitation;

Outcomes

Primary Outcomes

Fat-free mass

Time Frame: Baseline

Mass of the human body disregarding fat.

Quadriceps Force

Time Frame: Baseline

Quadriceps muscle strength measured during maximum voluntary contraction.

Handgrip strength

Time Frame: Baseline

Maximum voluntary manual holding force.

Total chest wall volume

Time Frame: Baseline

Total volume resulting from the sum of the volume of the pulmonary compartment of the costal, abdominal gradient of the costal and abdominal beds.

Oxygen uptake

Time Frame: Baseline

Consumption of oxygen during an effort.

Diaphragm mobility

Time Frame: Baseline

It is the diaphragmatic movement from the end of the expiration until the end of the inspiration, being able to be realized in tidal volume or starting from the total pulmonary capacity.

Diaphragm thickness

Time Frame: Baseline

Defined as a corpulence of the diaphragm muscle

Study Sites (1)

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