Role of Preoperative Tapentadol in Reduction of Perioperative Analgesic Requirement After Breast Conservative Surgery in Cancer Patients.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Intraoperative and postoperative morphine consumption
研究概览
简要总结
This study evaluated the preemptive analgesic efficacy of Tapentadol in reducing peri operative analgesic requirements among patients undergoing breast cancer surgery.
详细描述
A double blinded prospective RCT was conducted with 70 patients undergoing breast cancer surgery with 35 patients being studied with Administrated drug & other 35 as placebo. Intraoperative & postoperative morphine consumption was calculated and documented.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
盲法说明
The patient and doctor providing anesthesia were blinded.
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •18-60 years
- •Patients scheduled for breast conservation surgery -
排除标准
- •Patient refusal
- •CKD greater than 3
- •BMI greater than 35
- •Known drug allergy -
研究组 & 干预措施
Tapentadol
Control drug (Tapentadol )
干预措施: Tapentadol (Drug)
Placebo
Placebo sodium bicarbonate/ peppermint oil tablet
干预措施: Placebo (Other)
结局指标
主要结局
Intraoperative and postoperative morphine consumption
时间窗: During the course of surgery and up to 4 hours surgery
During the course of surgery and up to 4 hours surgery Intraoperative and postoperative morphine consumption.
次要结局
未报告次要终点