Skip to main content
MedPathMedPath Home
Clinical Trials/NCT00287781
NCT00287781
Completed
Not Applicable

A Double Blind Randomized Controlled of Placebo and Nebulized Lidocaine for Migraine Headache

Kern Medical Center1 site in 1 country150 target enrollmentJanuary 2002
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsMigraine Headache
DrugsLidocaine

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Migraine Headache
Sponsor
Kern Medical Center
Enrollment
150
Locations
1
Primary Endpoint
Resolution of symptoms
Status
Completed
Last Updated
18 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Migraine headaches have previously been shown to be responsive to intranasal lidocaine in a small study. Using a nebulizer to administer the drug would improve the feasibility of using the treatment. It would also spare the patient narcotics with their attendant side effects. Because of the potential for placebo effect a placebo control is necessary in this study.

Registry
clinicaltrials.gov
Start Date
January 2002
End Date
April 2006
Last Updated
18 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • •Meets IHS criteria for migraine

Exclusion Criteria

  • •Breast feeding
  • •Allergic to Lidocaine
  • •Worst or first Headache
  • •Abnormal neurological exam
  • •Substance abuse within 6 months
  • •Cardiac, liver or pulmonary disease
  • •Participation n another study within 30 days

Outcomes

Primary Outcomes

Resolution of symptoms

Secondary Outcomes

  • Improvement in 10 point pain score

Study Sites (1)

Loading locations...

Similar Trials

Completed
Not Applicable
Intranasal lidocaine effect for headache relief in patients at emergency departmentCondition 1: Headache. Condition 2: Migraine. Condition 3: headache.HeadacheMigraineOther headache syndromes
IRCT2013010712050N1Deputy of research, Shahid Sadoughi University of medical sciences90
Unknown
Phase 2
Topical Bimatoprost in the Treatment of MigraineMigraine DisordersHeadache Disorders
NCT03419715Manistee Partners70
Withdrawn
Phase 4
A Research Study of Greater Occipital Nerve Block as a Treatment for Acute Migraine AttacksMigraine
NCT03159000Thomas Jefferson University
Recruiting
Not Applicable
Closed-loop RTMS for Short-term Migraine PreventionMigraine Disorders
NCT06735768Brightmind.AI88
Completed
Phase 3
"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"HeadacheIntranasal Ketamine
NCT03081416Brooke Army Medical Center80