Establishing the Incidence of Tako-tsubo Cardiomyopathy in Scotland
- Conditions
- Takotsubo CardiomyopathyMyocardial Infarction
- Registration Number
- NCT03299569
- Lead Sponsor
- University of Aberdeen
- Brief Summary
Acute stress-induced (Takotsubo cardiomyopathy) presents like a heart attack and is triggered by intense emotional or physical stress. Although coronary arteries are unobstructed, it has been suggested that the risk of death is similar to a myocardial infarction. The purpose of the STARR study is to identify all cases of Takotsubo in Scotland since 2010 and assess its epidemiology and outcomes.
- Detailed Description
Public Health Scotland will identify all patients centrally coded under codes I42.8 (Other cardiomyopathies), I42.9 (Cardiomyopathy, unspecified) and I51.8 (Other ill-defined heart diseases), using the Community Health Index (CHI) numbers from January 2010. All identified CHI numbers will be thereafter cross-checked with their clinical data at participating health boards to confirm a diagnosis of takotsubo cardiomyopathy and a registry of all confirmed Takotsubo cases will be established.
Clinical data will be collected for all Takotsubo patients retrospectively and prospectively. This will be compared to two contemporaneous gender and age matched control populations:
1. a cohort of randomly selected individuals from the Scottish general population supplied by Public Health Scotland
2. patients with myocardial infarction (extracted through collaboration with, the High-STEACS investigators, NCT01852123).
Electronic data linkage will be performed by Public Health Scotland to assess outcomes, prescribing and scores of prediction.
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 800
- All patients diagnosed with Takotsubo cardiomyopathy
- NA
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mortality and morbidity of takotsubo syndrome 13 years To use a nation-wide cohort (and matched national-wide control populations) to establish the all-cause mortality and consequent all cause hospitalisation rates
- Secondary Outcome Measures
Name Time Method Specific causes of mortality and morbidity of takotsubo syndrome 13 years To use a nation-wide cohort (and matched national-wide control populations) to establish the specific causes of mortality and morbidities requiring subsequent hospitalisation
Trial Locations
- Locations (1)
Cardiac Research Office
🇬🇧Aberdeen, Scotland, United Kingdom