Bioavailability of oral curcumin ingestio
Completed
- Conditions
- Bioavailability of two different oral curcumin formulationsNot Applicable
- Registration Number
- ISRCTN83602901
- Lead Sponsor
- OmniActive Health Technologies Ltd
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 15
Inclusion Criteria
1. Normal healthy individuals
2. Age 18-55
3. Males and females
4. Must be able to perform required testing
5. Participants agreed to sign an informed consent form
Exclusion Criteria
1. Pregnancy
2. Use of prescription medications
3. Gastrointestinal conditions
4. Diabetics
5. Alcohol and/or substance abuse history, and/or allergies to turmeric or curcumin
6. Subjects consuming any foods or supplements containing curcumin
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma levels of major curcuminoids (curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin) will be evaluated at 0, 1, 2, 3, 4, 5, 6, 8 and 12 hours and 24 h. Peak plasma concentrations (TMax), areas under the plasma concentration-time curves (AUC0-6h, AUC0-12h and AUC0-24h), CMax and t max will be calculated. Relative absorption at 24h time point is helpful to observe normalization and safety of the product
- Secondary Outcome Measures
Name Time Method