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Clinical Trials/NCT00192998
NCT00192998UnknownNot Applicable

The Serotonergic Transmitter System in Dementia and Affective Disorders

Rigshospitalet, Denmark1 site in 1 country100 target enrollmentStarted: October 2003Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Enrollment
100
Locations
1
Study OverviewStudy DesignEligibility CriteriaInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The aim of this project is to examine the serotonergic transmitter system using functional imaging of the brain (positron emission tomography [PET]) to gain knowledge about early pathophysiological changes in Alzheimer's dementia and mood disorders.

Study Design

Study Type
Observational
Observational Model
Defined Population
Time Perspective
Other

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Moderate to severe Alzheimer's disease
  • •Individuals genetically predisposed to affective disorder
  • •Healthy gender and age matched controls

Exclusion Criteria

  • •Contraindications to magnetic resonance imaging (MRI)
  • •Use of psychoactive drugs
  • •Past or present affective disorder
  • •Other systemic diseases that may affect brain function

Investigators

Sponsor Class
Other

Study Sites (1)

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The Serotonergic Transmitter System in... | Clinical Trial