Effects of Low Dose Fentanyl Supplementation of Reduced Dose Propofol during Electroconvulsive Therapy

Phase 3

Completed

• Conditions: psychiatric patients who receiving electroconvulsive therapy; Hemodynamic response Propofol; Electroconvulsive therapy; Fentanyl; Thiopental; Seizure duration

• Registration Number: TCTR20201127005
• Lead Sponsor: Faculty of Medicine, Ramathibodi Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-08-31
• Study Start: 2020-11-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

adults, aged 18-65 years old and scheduled for bilateral ECT treatment.

Exclusion Criteria

patients who had a history of cardiovascular or cerebrovascular disease, poorly controlled hypertension, pregnancy, obesity (body mass index > 30 kg/m2), and had a contraindication to use thiopental, propofol, fentanyl, or succinylcholine.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
seizure duration Pre-dose, 1 min,2 min,3 min,4 min,5 min,6 min,7 min,8 min,9 min,10 min Post-dose EEG,blood pressure in,3 min,4 min,5 min,6 min,7 min,8 min,9 min,10 min Post-dose mmHg,blood pressure Pre-dose, 1,2,3,4,5,6,7,8,9,10 Post-dose mmHg,Oxygen satuaration in,3 min,4 min,5 min,6 min,7 min,8 min,9 min,10 min Post-dose pulse oxymeter ,heart rate in,3 min,4 min,5 min,6 min,7 min,8 min,9 min,10 min Post-dose EKG

Secondary Outcome Measures

Name	Time	Method
BIS index in,3 min,4 min,5 min,6 min,7 min,8 min,9 min,10 min Post-dose BIS