Effect of Blood Flow Restriction Training on the Subjective Perception of Pain in Hemophilic Arthropathy of the Knee Joint
Trial Snapshot
- Phase
- Not Applicable
- Status
- Enrolling By Invitation
- Sponsor
- Enrollment
- 12
- Locations
- 2
- Primary Endpoint
- Pain threshold
Study Overview
Brief Summary
In the course of a cross-over study design, 12 patients with hemophilic arthropathy will perform a training load on the knee extensor muscles. The subjects will each perform one intervention with blood flow restriction and one with a Sham-BFR intervention.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •patients with haemophilia
- •Ability for an exercise intervention
Exclusion Criteria
- •Sickle Cell Anemia
- •Intravascular stents/bypasses
- •Open Wounds/Infections of the lower extremity
Outcomes
Primary Outcomes
Pain threshold
Time Frame: Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention
Pain threshold measurement (PTT): The test determines the amount of pressure (in kg) over a given area in which a steadily increasing nonpainful pressure stimulus turns into a painful pressure sensation.
Quality of Life Score
Time Frame: Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention
Hemophilia Joint Health Score
Secondary Outcomes
No secondary outcomes reported
Investigators
Alexander Franz
Prinicipal Investigator
University Hospital, Bonn