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Clinical Trials/NCT07259356
NCT07259356Enrolling By InvitationNot Applicable

Effect of Blood Flow Restriction Training on the Subjective Perception of Pain in Hemophilic Arthropathy of the Knee Joint

University Hospital, Bonn2 sites in 1 country12 target enrollmentStarted: August 1, 2024Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Enrolling By Invitation
Sponsor
Enrollment
12
Locations
2
Primary Endpoint
Pain threshold

Study Overview

Brief Summary

In the course of a cross-over study design, 12 patients with hemophilic arthropathy will perform a training load on the knee extensor muscles. The subjects will each perform one intervention with blood flow restriction and one with a Sham-BFR intervention.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Crossover
Primary Purpose
Treatment
Masking
Single (Outcomes Assessor)

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • patients with haemophilia
  • Ability for an exercise intervention

Exclusion Criteria

  • Sickle Cell Anemia
  • Intravascular stents/bypasses
  • Open Wounds/Infections of the lower extremity

Outcomes

Primary Outcomes

Pain threshold

Time Frame: Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention

Pain threshold measurement (PTT): The test determines the amount of pressure (in kg) over a given area in which a steadily increasing nonpainful pressure stimulus turns into a painful pressure sensation.

Quality of Life Score

Time Frame: Pre- (Baseline, before Exercise) to immediately Post-Intervention (after the exercise training intervention) and 24 hours after intervention

Hemophilia Joint Health Score

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor
University Hospital, Bonn
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Alexander Franz

Prinicipal Investigator

University Hospital, Bonn

Study Sites (2)

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