Effectiveness of Pharmaceutical Interventions in Hospitalized Patients

Not Applicable

Completed

• Conditions: Safety Issues
• Interventions: Other: Pharmaceutical intervention

• Registration Number: NCT04800900
• Lead Sponsor: Federal University of Bahia

Brief Summary

The presence of multimorbidities is very common among the elderly, which become major consumers of medicines. The process of prescribing medicines for the elderly should be done with caution, as the use of some medications may present more risks than benefits in this range age. Potentially inappropriate prescribing for the elderly has become a global concern for the promotion of an adequate pharmacotherapy, it becomes essential to be aware of the effectiveness and safety of medicines and the knowledge of which drugs whose risks of serious adverse reactions outweigh the benefit of your referral. In this sense, the present study has aim to evaluate the effectiveness of pharmaceutical interventions in frequency of omission of drugs with proven efficacy for cardiovascular diseases and promotion of treatment prescription inappropriate and polypharmacy. A prospective quasi experimental before and after study will be carried out in elderly patients diagnosed with cardiovascular disease admitted to the Ana Nery hospital, Salvador, Bahia, Brazil. A convenience sample will be collected, the data will be released and revised in a database built in the SPSS software and analyzed in the program statistic R and SPSS. At the end of the study, it is expected a decrease in the frequency of omission of medications and promotion of prescription drugs inappropriate.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-02-02
• Study Start: 2021-02-04
• Study First Submitted QC: 2021-03-14
• Study First Posted: 2021-03-16
• Primary Completion: 2022-01-30
• Study Completion: 2022-01-30
• Status Verified: 2022-04
• Last Update Submitted: 2022-04-10
• Last Update Posted: 2022-04-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 332

Inclusion Criteria

• Clinical diagnosis of cardiovascular disease
• Discharge after 24 hours

Exclusion Criteria

* Death

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Pharmaceutical intervention	Pharmaceutical intervention	A pharmacist will analyse patient's prescription, identify if there is prescribing omission and inappropriated drug prescribed and when necessary will require to doctors

Primary Outcome Measures

Name	Time	Method
Effectiveness of pharmaceutical interventions measured by proportion of accepted interventions and all interventions	The acceptance of all pharmaceutical interventions related to inappropriate prescribed drugs and omission of prescription during the hospitalization of the patient will be evaluated, through study completion, an average of 1 year

Secondary Outcome Measures

Name	Time	Method
Incidence of omission of prescription drugs with proven efficacy for cardiovascular diseases measured by the START criteria	First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year
Incidence of polypharmacy in elderly people with cardiovascular diseases measured by prescription containing five or more drugs	First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year
Incidence of potentially inappropriate drug prescription in elderly people with cardiovascular diseases measured by the Beers criteria	First prescription after 24 hours of admission, last prescription and discharge prescription through study completion, an average of 1 year

Trial Locations

Locations (1)

Hospital Ana Nery; 🇧🇷 Salvador, Bahia, Brazil