ISRCTN32891249已完成3 期
A randomised trial of adjuvant procarbazine, CCNU, vincristine chemotherapy in patients with highly anaplastic oligodendroglioma (BR11) - EORTC
Medical Research Council (MRC) (UK)0 个研究点目标入组 368 人开始时间: 2000年4月6日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 368
研究概览
简要总结
2006 Results article in http://www.ncbi.nlm.nih.gov/pubmed/16782911 results 2007 Results article in http://www.ncbi.nlm.nih.gov/pubmed/18089866 results 2007 Results article in http://www.ncbi.nlm.nih.gov/pubmed/18089867 results 2009 Results article in http://www.ncbi.nlm.nih.gov/pubmed/19224764 results
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Newly diagnosed anaplastic oligodendroglioma, or oligoastrocytoma (with 25% or more oligodendral elements); including patients treated with surgery only for a low grade oligoastrocytoma or oligodendroglioma who are diagnosed with anaplastic tumour at the time of recurrence
- •2. At least three of five histologic anaplastic features: high cellularity, nuclear abnormalities, mitoses, endothelial abnormalities and necrosis, as diagnosed by the local pathologist
排除标准
- •Does not meet inclusion criteria
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