Assist Control Versus Pressure Support Modes for Domiciliary Noninvasive Ventilation

Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche0 sites100 target enrollmentJanuary 2006

ConditionsChronic Respiratory Failure

Overview

Phase: N/A
Intervention: Not specified
Conditions: Chronic Respiratory Failure
Sponsor: Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche
Enrollment: 100
Primary Endpoint: PaO2
Status: Completed
Last Updated: 15 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

Noninvasive ventilation is a therapeutic option in some patients with chronic respiratory failure. Patients usually ventilate during nightime with a domiciliary ventilator either in assist control or in pressure support mode.

The aim of this study is to compare the clinical efficacy and the tolerance of assist control and pressure support modes during domiciliary noninvasive ventilation in patients with chronic respiratory failure.

Detailed Description

Registry

clinicaltrials.gov

Start Date

January 2006

End Date

October 2009

Last Updated

15 years ago

Study Type

Interventional

Study Design

Crossover

Sex

All

Investigators

Sponsor

Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche

Eligibility Criteria

Inclusion Criteria

•Chronic respiratory failure
•Clinical symptoms of chronic alveolar hypoventilation
•PaCO2 ≥ 45 mmHg in case of restrictive pulmonary disorder or PaCO2 ≥ 55 mmHg in case or obstructive pulmonary disorder

Exclusion Criteria

•Clinical exacerbation during the three previous weeks
•Previous treatment by domiciliary non invasive ventilation
•Previous treatment by non invasive ventilation for acute respiratory failure during the 3 previous months
•Bronchiectasis
•Duchenne muscular dystrophy
•Amyotrophic lateral sclerosis