跳至主要内容
临床试验/NCT07286981
NCT07286981已完成不适用

Assessment of the Glycemic Index of Various Saudi Date Cultivars and Date-based Products. in Healthy Adults

King Saud University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年8月16日最近更新:

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
Glycemic Index

研究概览

简要总结

Dates are widely consumed worldwide and hold substantial cultural importance in many Middle Eastern communities. Despite growing interest in measuring the glycemic response and glycemic index of foods for both research and practical applications, studies examining the glycemic properties of different date cultivars and their derived products remain limited. This study aims to determine the glycemic index (GI) and glycemic load (GL) of commonly consumed Saudi date cultivars and their derived products in healthy subjects, and to evaluate their potential impact on postprandial glucose responses. The study will consist of 4 phases as follows: phase 1: Date varieties at Tamer stage; phase 2: date varieties at Rutab stage; phase 3: Date's debs; phase 4: Date's paste. For each phase, ten subjects will be asked to attend the laboratory in the morning after an overnight fast on several occasions. Each visit will be separated from the next by a "washout" day. The reference food, 50 g of glucose dissolve in 250 ml water will be tested on 3 alternating days to diminish day to day variation of glucose tolerance. 50g equivalent carbohydrates of dates will be consumed with 250 ml of water. Participants will be blinded to the type of the dates. Glucose will be measured in capillary blood samples following the two hours of the test meal consumption, at 15 min interval (0, 15, 30, 45, 60, 90 and 120 min) . A qualified technician will perform all blood glucose measurements.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy adults aged 18 to 55 years
  • Normotensive (normal blood pressure)
  • Normal fasting glucose levels
  • Not taking any prescription medication
  • Able and willing to provide written informed consent

排除标准

  • Morbid obesity (BMI > 40 kg/m²)
  • Pre-diabetic status
  • Pregnancy
  • Any gastrointestinal disorders
  • History of gastroenteritis within the preceding six months
  • Previous gastrointestinal surgeries
  • Presence of chronic conditions (e.g., asthma, rheumatoid arthritis)
  • Presence of acute illnesses (e.g., respiratory or urinary tract infections)

结局指标

主要结局

Glycemic Index

时间窗: Baseline (fasting) and up to 120 minutes post-consumption on each test day.

The glycemic index of each date cultivar and date-based product will be determined on designated test days by calculating the incremental area under the blood glucose response curve (iAUC) over the 120-minute postprandial period following consumption of a portion containing 50 g of available carbohydrates, relative to the iAUC of a reference glucose solution. Blood glucose measurements will be obtained at baseline (fasting) and at predefined time points up to 120 minutes after ingestion.

次要结局

  • Glycemic Load (GL) of Fresh and Processed Date Products(Baseline (fasting) and up to 120 minutes post-consumption on each test day.)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Maha Alhussain

Associate Professor

King Saud University

研究点 (1)

Loading locations...

相似试验