To evaluate the effect of Ayurveda treatment Compared to allopath Treatment in the Management of Amavata (Rheumatoid Arthritis)
- Conditions
- Rheumatoid arthritis with rheumatoid factor, unspecified. Ayurveda Condition: AMAVATAH,
- Registration Number
- CTRI/2023/05/053230
- Lead Sponsor
- All India institute of ayurveda
- Brief Summary
Rheumatoid Arthritis (RA) is a common systemic autoimmune disease that 1% of the world’s population is suffering from it. Epidemiological surveys by WHO –COPCORD(WHO community oriented program for control of rheumatoid disease) shows a prevalence of 0.45% in urban India and 0.7%in rural population, The disease, in addition to reducing the average life expectancy of patients, is associated with significant morbidity. So that 50% of RA patients are not able to continue their jobs after ten years of illness .
In Ayurveda commonly used in all the diseases is Samshodhana and Shamana. Samshodhana indicates the Dosha eliminating process, Whereas Shaman brings into equilibrium the aggravated Doshas in the body. Each type of procedure is having its equal importance in their respective way.
In modern medical science with extreme advancement in diagnostic approach, It is a challenging disease for the physicians and medical field. Disease-modifying anti-rheumatic drugs (DMARDs) are standard medication for RA patients, methotrexate is one of the commonly used drug to suppress autoimmune response but its side effects is notorious
Amavata is one of the devastating diseases that cause permanent disability. The condition is named for its two main pathogenic components, Ama and Vata. these two factors simultaneously take part in theSamprapti making it difficult to treat. According to samprapti wherever this Ama gets localized in the body tissue or joints, it can lead to production of pain, stiffness, swelling, tenderness in related joints.[8] It is not just a problem of the locomotor system; it is also a systemic disease.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 78
- 1.Chronicity: < 5 years.
- 2.Presence of minimum 2 clinical features of Amavata (SandhiShoola,Sandhi Stabdhata) 3.RA (seropositive ) 4.The subjects who will fullfill the ACR-EULAR Criteria:2010 (presence of total score ≥ 6 from criteria) 5.Preferably freshly diagnosed cases of Rheumatoid arthritis / old cases after the washout period of one month.
- Juvenile R.A. 2.Chronicity: > 5 years.
- 3.Not willing to participate in the study.
- 4.Patients with tuberculosis ,Hypertension ,pregnant women.
- Patients unfit for Swedana & Basti.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in disease activity DAS -28 Reduction in disease activity DAS -28 | • Relief in Cardinal Symptoms such as Pain (Shoola), shotha (swelling), stabdhata (stiffness) ,Range of movements as compared to earlier life style in the patients of Amavata [Rheumatoid artheritis]. • Relief in Cardinal Symptoms such as Pain (Shoola), shotha (swelling), stabdhata (stiffness) ,Range of movements as compared to earlier life style in the patients of Amavata [Rheumatoid artheritis]. Reduction in disease activity DAS -28 | • Relief in Cardinal Symptoms such as Pain (Shoola), shotha (swelling), stabdhata (stiffness) ,Range of movements as compared to earlier life style in the patients of Amavata [Rheumatoid artheritis].
- Secondary Outcome Measures
Name Time Method Development of a comprehensive Ayurveda score for Amavata (CASA). • Improvement in HAQ-DI the quality of life .
Trial Locations
- Locations (1)
All India institute of ayurveda
🇮🇳Delhi, DELHI, India
All India institute of ayurveda🇮🇳Delhi, DELHI, IndiaPoonam vermaPrincipal investigator8377885153dr.poonamverma235@gmail.com