Outcomes After Perioperative Stroke Following Cardiac Surgery
试验速览
- 阶段
- 不适用
- 入组人数
- 906
- 试验地点
- 1
- 主要终点
- Death
研究概览
简要总结
Perioperative stroke is a devastating complication of cardiac surgery that is currently poorly characterized but occurs in 1-5% of patients and is associated with poor outcomes including increased mortality. Given the uncommon nature of this complication, relatively little is known about which factors predict these outcomes among those who experience a perioperative stroke. The study objectives are to identify predictors of mortality, length of stay and discharge disposition after perioperative stroke in cardiac surgery using the prospectively-collected American College of Surgeons National Surgical Quality Improvement Program database between 2005 and 2020.
详细描述
BACKGROUND Perioperative stroke is a devastating complication of cardiac surgery that is currently poorly characterized. Perioperative stroke is a cerebrovascular event that occurs after cardiac surgery, and affects between1-5% of patients. The current literature has identified that patients who experience a stroke after surgery have a higher rate of mortality, length of stay and discharge to a facility, but given the rare nature of this complication less is known about which factors predict these outcomes among those who experience a perioperative stroke.
OBJECTIVES
- Derive and externally validate risk prediction models for mortality (primary outcome), adverse discharge, and length of stay after perioperative stroke.
- Describe temporal trends in mortality after perioperative stroke between 2005 and 2020.
METHODS This study is a retrospective analysis of the prospectively-collected American College of Surgeons National Surgical Quality Improvement Program database between 2004 and 2020. The study cohort will be extracted from the NSQIP database and include all patients who experienced a stroke within 30 days of surgery and who underwent a cardiac surgical procedure.
STUDY POPULATION Patients who underwent any cardiac surgical procedure and who experienced a perioperative stroke in the NSQIP database between 2005 and 2020 will be included.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Experienced a perioperative stroke
- •Underwent cardiac surgery
排除标准
- 未提供
结局指标
主要结局
Death
时间窗: Within 30 days of surgery
Death
次要结局
- Adverse discharge(Within 30 days of surgery)
- Length of stay(Within 30 days of surgery)
研究者
Alana Flexman
Principal Investigator
University of British Columbia
