Respiratory Complications After Laparoscopic Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Arterial oxygen tension 2 hours after surgery
研究概览
简要总结
The purpose of this study is to describe the magnitude of respiratory complications after laparoscopic hysterectomy and cholecystectomy.
详细描述
The purpose of this study is to describe change in pulmonary function and incidence of respiratory complications after laparoscopic surgery.
The investigators will include 60 women scheduled for laparoscopic hysterectomy or cholecystectomy. The investigators will measure the pulmonary function by different methods during and for 2 hours after surgery. Moreover, the incidence of respiratory complications including pneumonia, respiratory failure and radiologically verified atelectasis will be registered.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •> 45 years old
- •Scheduled for laparoscopic cholecystectomy or laparoscopic hysterectomy
排除标准
- •Weight < 50 kg
- •Pregnant or nursing
- •Cardiac failure
- •Renal failure
- •Inability to breath through a facial mask
- •Inability to give informed consent
- •Inability to keep arterial oxygen saturation above 90% without supplemental oxygen
结局指标
主要结局
Arterial oxygen tension 2 hours after surgery
时间窗: 2 hours after end of surgery
Change in arterial oxygen tension 2 hours after surgery
次要结局
- Arterial oxygen saturation 2 hours after surgery(2 hours after surgery)
- Pneumonia(Participants will be followed for the duration of hospital stay, an expected average of 3 days)
- Respiratory frequency 2 hours after surgery(2 hours after surgery)
- Oxygenation index 2 hours after surgery(2 hours after end of surgery)
- FEV1 and FVC 2 hours after surgery(2 hours after end of surgery)
- Pulmonary shunt 2 hours after surgery(2 hours after end of surgery)
- Ventilation-perfusion ratio 2 hours after surgery(2 hours after end of surgery)
- Oxygen supplement at discharge from the postanesthesia care unit(At discharge from the postanesthesia care unit, which will be approximately 2 hours after surgery)
- Connection between pulmonary shunt and need for oxygen supplement(2 hours postoperatively and at discharge from the postanesthesia care unit)
- FEV1 and FVC 24 hours after surgery(24 hours after surgery)
- Pulmonary shunt 24 hours after surgery(24 hours after surgery)
- Ventilation-perfusion ratio 24 hours after surgery(24 hours after surgery)
- Arterial oxygen saturation 24 hours after surgery(24 hours after surgery)
- Respiratory frequency 24 hours after surgery(24 hours after surgery)
- Length of stay(Participants will be followed for the duration of hospital stay, an expected average of 3 days)
- Respiratory failure after surgery(Participants will be followed for the duration of hospital stay, an expected average of 3 days)
- Atelectasis(Participants will be followed for the duration of hospital stay, an expected average of 3 days)
- High temperature(Participants will be followed for the duration of hospital stay, an expected average of 3 days)
研究者
Anne Kathrine Staehr
Research Assistant
Herlev Hospital