UNC Metastatic Cancer Radiation Therapy Registry

Recruiting

• Conditions: Metastatic Cancer; Cancer
• Interventions: Radiation: Radiation therapy

• Registration Number: NCT06306924
• Lead Sponsor: UNC Lineberger Comprehensive Cancer Center

Brief Summary

The purpose of this registry is to collect clinical data from participants attending UNC Hospitals who present with metastatic cancer and are evaluated to receive radiation therapy as part of their standard of care treatment. The goal of this study is to provide a foundation for studies designed to identify projects across the translational continuum related to metastatic cancer and radiation therapy treatment. The relevant clinical data will be linked to patient-reported outcomes (PROs) thus allowing for a unique and robust dataset. Ultimately, this registry will provide current and future studies with the ability to analyze the correlation of radiation therapy regimens with metastatic cancer outcomes.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-03-05
• Study First Submitted QC: 2024-03-05
• Study First Posted: 2024-03-12
• Study Start: 2024-04-21
• Status Verified: 2025-04
• Last Update Submitted: 2025-04-28
• Last Update Posted: 2025-05-01
• Primary Completion: 2033-05
• Study Completion: 2033-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

Written informed consent was obtained to participate in the study and HIPAA

Authorization for release of personal health information. Ability to understand and willingness to sign informed consent

Diagnosed with or is suspected to have metastatic cancer.

Age ≥ 18 years at the time of consent.

Evaluated to receive radiation therapy as part of their standard-of-care treatment plan.

Exclusion Criteria

All participants must not meet any of the following exclusion criteria prior to enrollment to participate in this study:

Any serious medical or psychiatric disorder that would interfere with the participant's ability to give informed consent.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Palliative radiation therapy	Radiation therapy	Subjects who are with metastatic cancer receive palliative radiation therapy.

Primary Outcome Measures

Name	Time	Method
Clinical Data	Up to 1 month	Clinical data and radiological assessments from participants with metastatic cancer receiving radiation therapy as a part of the standard of care will be collected.

Secondary Outcome Measures

Name	Time	Method
Patient reported outcomes (PRO)	Baseline, 1 month, 3 months, 6 months, 9 months, and 12 months	Patient reported outcomes (PRO) from participants will be collected at different time points.

Trial Locations

Locations (1)

Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill; 🇺🇸 Chapel Hill, North Carolina, United States