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Clinical Trials/NCT05615246
NCT05615246
Terminated
N/A

An Open Label, Multi-Center, Retrospective and Prospective Evaluation of Exactech Humeral Reconstruction Prosthesis of Shoulder Arthroplasty

Exactech1 site in 1 country4 target enrollmentSeptember 5, 2018

Overview

Phase
N/A
Intervention
Not specified
Conditions
Osteoarthritis Shoulder
Sponsor
Exactech
Enrollment
4
Locations
1
Primary Endpoint
SST-12
Status
Terminated
Last Updated
last year

Overview

Brief Summary

The objective of this study is to collect and evaluate long-term clinical outcomes data in order to better understand the safety and performance of the Equinoxe Humeral Reconstruction Prosthesis in shoulder arthroplasty over time. This study will follow subjects for a period of up to 10 years post-surgery.

Registry
clinicaltrials.gov
Start Date
September 5, 2018
End Date
September 25, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Exactech
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient is indicated for shoulder arthroplasty (or has previously undergone shoulder arthroplasty)
  • Patient is at least 21 years of age
  • Patient is expected to survive at least 2 years beyond surgery
  • Patient is willing to participate by complying with pre- and postoperative visit requirements
  • Patient is willing and able to read and sign a study informed consent form

Exclusion Criteria

  • Osteomyelitis of the proximal humerus or scapula; if a systemic infection or a secondary remote infection is suspected or confirmed, implentation should be delayed until infection is resolved
  • Inadequate or malformed bone that precludes adequate support or fixation of the prosthesis
  • Neuromuscular disorders that do not allow control of the joint
  • SIgnigicant injury to the brachial plexus
  • Non-functional deltoid muscles
  • Patient's age, weight, or activity level would cause the surgeon to expect early failure of the system
  • The patient is unwilling or unable to comply with the post-operative care instructions
  • Alcohol, drug, or other subtance abuse
  • Any disease state that could adversely affect the function or longevity of the implant
  • Patient is pregnant

Outcomes

Primary Outcomes

SST-12

Time Frame: Through study completion, an average of 1 per year

Shoulder Simple Test (SST) - 12 questions with yes/no responses that measure shoulder pain and function from a patient's perspective - 12 yes corresponds to 100%

SPADI

Time Frame: Through study completion, an average of 1 per year

Shoulder Pain and Disability Index (SPADI) -13 questions assessing about pain scale (5 questions) and disability scale (8 questions) where 0 indicates no pain/no difficulty and 10 indicates worst pain imaginable/so difficult it requires help while performin these activities

Constant

Time Frame: Through study completion, an average of 1 per year

Constant Shoulder Score - 100 points scale about pain, Activities of daily living, Strength test, and Range of Motions questions about shoulder where 100 % corresponds to the highest pain

UCLA

Time Frame: Through study completion, an average of 1 per year

University of California Los Angeles Shoulder Score (UCLA) - 5 Items score which combines both physician (3 items) and patient assessment (2 items) whith a total range from 0-35 where 0 indicates worse shoulder function and 35 better shoulder function outcomes

ASES

Time Frame: Through study completion, an average of 1 per year

American Shoulder and Elbow Surgeons Score (ASES) - 100 points scale about shoulder pain and performance evaluation in activities of daily living where 100 indicates the best shoulder condition

MSTS

Time Frame: Through study completion, an average of 1 per year

Musculoskeletal Tumor Society (MSTS) - 30 points \[6 times (range 0-5)\], simple measure of the upper extremity function (Humeral Reconstruction Stem only) - The maximum corresponds to the best score

TESS

Time Frame: Through study completion, an average of 1 per year

Toronto Extremity Salvage Score (TESS) - Patient functional assessment following for surgery for musculoskeletal tumors (Humeral Reconstruction Stem only) - 100-point score where higher score indicates a better outcome

Study Sites (1)

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