Prospective Cohort Study of Neuromyelitis Optica Spectrum Disorders (NMOSD)
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 4,000
- Locations
- 5
- Primary Endpoint
- Variations in Serum Sex Hormones
Study Overview
Brief Summary
This study aims to characterize sex hormone alterations and their potential clinical significance in NMOSD patients from Southern China through comprehensive hormonal profiling.
Detailed Description
This study is a prospective cohort study, aiming to explore the characteristics of sex hormone levels in patients with neuromyelitis optica spectrum disorder (NMOSD). It plans to include 2,000 patients with NMOSD and 2,000 healthy controls, and conduct a 3-year follow-up. By regularly collecting data such as serum sex hormone levels, imaging, neurological function scales, and various biomarkers, the differences between the two groups will be compared and analyzed to reveal the role of sex hormones in NMOSD and their association with disease activity.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Variations in Serum Sex Hormones
Time Frame: Baseline, 6 months, 12 months, 18 months, 24 months, 30 months, 36 months.
Secondary Outcomes
No secondary outcomes reported
Investigators
Li Shiyong
Xiamen Traditional Chinese Medicine Hospital
Xiamen Hospital of Traditional Chinese Medicine