Effects of a vitamin D analog in type 1 diabetic childre
Not Applicable
- Conditions
- type 1 diabetes.Insulin-dependent diabetes mellitus
- Registration Number
- IRCT201205159753N1
- Lead Sponsor
- Endocrinology & Metabolism Research Institute, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Age 8-18 years; Consecutively diagnosed as having T1DM according to the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus criteria; Without DKA; Duration of clinical disease (since the beginning of insulin therapy) less than 8 weeks; Without any medical co-morbidities or any other major chronic disease; Being on a stable diabetic diet therapy at least since 1 week ago
Exclusion criteria: Cholecalciferol, calcium, multi-vitamin or mineral supplementation during the previous 3 months; Consuming some vitamin D-fortified foods; Hypercalcemia defined as total serum calcium higher than 10.8 mg/dl, at baseline or during follow-up.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum fasting C-peptide. Timepoint: months 0, 3, and 6 after intervention. Method of measurement: ELISA.
- Secondary Outcome Measures
Name Time Method Dose of insulin requirement. Timepoint: months 0, 3, and 6 after intervention. Method of measurement: Adjusted dose of insulin according to patients' blood glucose records.